Human pathophysiological adaptations to the space environment

GC Demontis, MM Germani, EG Caiani… - Frontiers in …, 2017 - frontiersin.org
Space is an extreme environment for the human body, where during long-term missions
microgravity and high radiation levels represent major threats to crew health. Intriguingly …

Space radiation: the number one risk to astronaut health beyond low earth orbit

JC Chancellor, GBI Scott, JP Sutton - Life, 2014 - mdpi.com
Projecting a vision for space radiobiological research necessitates understanding the nature
of the space radiation environment and how radiation risks influence mission planning …

Influence of microgravity on apoptosis in cells, tissues, and other systems in vivo and in vitro

B Prasad, D Grimm, SM Strauch, GS Erzinger… - International journal of …, 2020 - mdpi.com
All life forms have evolved under the constant force of gravity on Earth and developed ways
to counterbalance acceleration load. In space, shear forces, buoyance-driven convection …

Limitations in predicting the space radiation health risk for exploration astronauts

JC Chancellor, RS Blue, KA Cengel… - npj …, 2018 - nature.com
Despite years of research, understanding of the space radiation environment and the risk it
poses to long-duration astronauts remains limited. There is a disparity between research …

Key points for the development of antioxidant cocktails to prevent cellular stress and damage caused by reactive oxygen species (ROS) during manned space …

X Gómez, S Sanon, K Zambrano, S Asquel… - npj …, 2021 - nature.com
Exposure to microgravity and ionizing radiation during spaceflight missions causes
excessive reactive oxygen species (ROS) production that contributes to cellular stress and …

Space radiation protection: destination Mars

M Durante - Life sciences in space research, 2014 - Elsevier
National space agencies are planning a human mission to Mars in the XXI century. Space
radiation is generally acknowledged as a potential showstopper for this mission for two …

The case for biotech on Mars

SN Nangle, MY Wolfson, L Hartsough, NJ Ma… - Nature …, 2020 - nature.com
The case for biotech on Mars | Nature Biotechnology Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

Neuro-consequences of the spaceflight environment

SD Mhatre, J Iyer, S Puukila, AM Paul… - Neuroscience & …, 2022 - Elsevier
As human space exploration advances to establish a permanent presence beyond the Low
Earth Orbit (LEO) with NASA's Artemis mission, researchers are striving to understand and …

Effects of ionizing radiation on the heart

M Boerma, V Sridharan, XW Mao, GA Nelson… - … Research/Reviews in …, 2016 - Elsevier
This article provides an overview of studies addressing effects of ionizing radiation on the
heart. Clinical studies have identified early and late manifestations of radiation-induced …

Aspergillus niger Spores Are Highly Resistant to Space Radiation

M Cortesão, A De Haas, R Unterbusch… - Frontiers in …, 2020 - frontiersin.org
The filamentous fungus Aspergillus niger is one of the main contaminants of the
International Space Station (ISS). It forms highly pigmented, airborne spores that have thick …