Identifying parameter regions for multistationarity

C Conradi, E Feliu, M Mincheva… - PLoS computational …, 2017 - journals.plos.org
Mathematical modelling has become an established tool for studying the dynamics of
biological systems. Current applications range from building models that reproduce …

[HTML][HTML] Advancing Mathematical Epidemiology and Chemical Reaction Network Theory via Synergies Between Them

F Avram, R Adenane, M Neagu - Entropy, 2024 - mdpi.com
Our paper reviews some key concepts in chemical reaction network theory and
mathematical epidemiology, and examines their intersection, with three goals. The first is to …

Large deviations theory for Markov jump models of chemical reaction networks

A Agazzi, A Dembo, JP Eckmann - The Annals of Applied Probability, 2018 - JSTOR
We prove a sample path Large Deviation Principle (LDP) for a class of jump processes
whose rates are not uniformly Lipschitz continuous in phase space. Building on it, we further …

Investigating synergies between chemical reaction networks (CRN) and mathematical epidemiology (ME), using the Mathematica package Epid-CRN

F Avram, R Adenane, AD Halanay… - arXiv preprint arXiv …, 2024 - arxiv.org
In this essay, we investigate some relations between Chemical Reaction Networks (CRN)
and Mathematical Epidemiology (ME) and report on several pleasant surprises which we …

Robust persistence and permanence of polynomial and power law dynamical systems

JD Brunner, G Craciun - SIAM Journal on Applied Mathematics, 2018 - SIAM
A persistent dynamical system in R^d_>0 is one whose solutions have positive lower
bounds for large t, while a permanent dynamical system in R^d_>0 is one whose solutions …

On Persistence of Some -Endotactic Chemical Reaction Networks

X Zhang, C Gao, D Dochain - IEEE Transactions on Automatic …, 2023 - ieeexplore.ieee.org
Motivated by the concept of the endotactic network, a kind of special geometric structure in
chemical reaction networks developed for persistence analysis, we propose a new notion …

Endotactic networks and toric differential inclusions

G Craciun, A Deshpande - SIAM Journal on Applied Dynamical Systems, 2020 - SIAM
An important dynamical property of biological interaction networks is persistence, which
intuitively means that “no species goes extinct." It has been conjectured that dynamical …

Conditions for extinction events in chemical reaction networks with discrete state spaces

MD Johnston, DF Anderson, G Craciun… - Journal of mathematical …, 2018 - Springer
We study chemical reaction networks with discrete state spaces and present sufficient
conditions on the structure of the network that guarantee the system exhibits an extinction …

[HTML][HTML] Uniform and strict persistence in monotone skew-product semiflows with applications to non-autonomous Nicholson systems

R Obaya, AM Sanz - Journal of Differential Equations, 2016 - Elsevier
We determine sufficient conditions for uniform and strict persistence in the case of skew-
product semiflows generated by solutions of non-autonomous families of cooperative …

Symbolic analysis of multiple steady states in a MAPK chemical reaction network

D Lichtblau - Journal of Symbolic Computation, 2021 - Elsevier
We consider the problem of analyzing chemical reaction networks that may allow multiple
positive steady states. We use tools from “classical” computer algebra (Gröbner bases over …