The replacement of fossil resources that currently provide more than 90% of our energy
needs and feedstocks of the chemical industry in combination with reduced emission of …

Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …

The transition from a fossil fuel-based economy to a bio-based economy necessitates the
exploitation of synergies, scientific innovations and breakthroughs, and step changes in the …

Reduced nicotinamide adenine dinucleotide phosphate (NADPH) is an essential electron
donor in all organisms. It provides the reducing power that drives numerous anabolic …

Biomass can be classified broadly as all the matter on the earth's surface of recent biological
origin. 1 Biomass includes plant materials such as trees, grasses, agricultural crops, algal …

Recent concerns over the sustainability of petrochemical-based processes for production of
desired chemicals have fueled research into alternative modes of production. Metabolic …

Hydroxypropionic acid (3-HP) is a valuable platform chemical that can be produced
biologically from glucose or glycerol. This review article provides an overview and the …

NADPH is an essential cofactor for the biosynthesis of several high-value chemicals,
including isoprenoids, fatty acid-based fuels, and biopolymers. Tunable control over all …

Engineering cells to produce valuable metabolic products is hindered by the slow and
laborious methods available for evaluating product concentration. Consequently, many …

Malonyl-CoA is the building block for fatty acid biosynthesis and also a precursor to various
pharmaceutically and industrially valuable molecules, such as polyketides and biopolymers …