Borrelia burgdorferi sensu lato (Bbsl) is a bacterial species complex that includes the
etiological agents of the most frequently reported vector-borne disease in the Northern …

All members of the Borrelia genus that have been examined harbour a linear chromosome
that is about 900 kbp in length, as well as a plethora of both linear and circular plasmids in …

Borrelia burgdorferi sensu stricto isolates from patients with erythema migrans in Europe
and the United States were compared by genotype, clinical features of infection, and …

Borrelia burgdorferi sensu lato species complex is capable of establishing persistent
infections in a wide variety of species, particularly rodents. Infection is asymptomatic or mild …

Persistent genetic variation within populations presents an evolutionary problem, as natural
selection and genetic drift tend to erode genetic diversity. Models of balancing selection …

Lyme borreliosis (LB) is the most common tick-borne disease caused by the spirochete
Borrelia burgdorferi in North America and Borrelia afzelii or Borrelia garinii in Europe and …

Lyme borreliosis is the most prevalent tick-borne disease in the United States, infecting~
476,000 people annually. Borrelia spp. spirochetal bacteria are the causative agents of …

The major human spirochetal pathogens (Leptospira, Borrelia, and Treponema) are difficult
to diagnose and lack vaccines to prevent infections. Infection by these spirochetes does not …

The bacterial genus, Borrelia, is comprised of vector-borne spirochete species that infect
and are transmitted from multiple host species. Some Borrelia species cause highly …

Borrelia burgdorferi is one of the few extracellular pathogens capable of establishing
persistent infection in mammals. The mechanisms that sustain long-term survival of this …