Impact of endemic infections on HIV susceptibility in sub-Saharan Africa
Human immunodeficiency virus (HIV) remains a leading cause of global morbidity with the
highest burden in Sub-Saharan Africa (SSA). For reasons that are incompletely understood …
highest burden in Sub-Saharan Africa (SSA). For reasons that are incompletely understood …
Impact of helminth infections on female reproductive health and associated diseases
A growing body of knowledge exists on the influence of helminth infections on allergies and
unrelated infections in the lung and g astro i ntestinal (GI) mucosa. However, the bystander …
unrelated infections in the lung and g astro i ntestinal (GI) mucosa. However, the bystander …
Helminth antigens differentially modulate the activation of CD4+ and CD8+ T lymphocytes of convalescent COVID-19 patients in vitro
Background The coronavirus disease 2019 (COVID-19) is a respiratory disease caused by
SARS-CoV-2, a recently discovered strain of coronavirus. The virus has spread rapidly …
SARS-CoV-2, a recently discovered strain of coronavirus. The virus has spread rapidly …
Helminth Infection–Induced Increase in Virtual Memory CD8 T Cells Is Transient, Driven by IL-15, and Absent in Aged Mice
Abstract CD8 virtual memory T (T VM) cells are Ag-naive CD8 T cells that have undergone
partial differentiation in response to common γ-chain cytokines, particularly IL-15 and IL-4. T …
partial differentiation in response to common γ-chain cytokines, particularly IL-15 and IL-4. T …
Depletion and activation of mucosal CD4 T cells in HIV infected women with HPV-associated lesions of the cervix uteri
Background The burden of HPV-associated premalignant and malignant cervical lesions
remains high in HIV+ women even under ART treatment. In order to identify possible …
remains high in HIV+ women even under ART treatment. In order to identify possible …
Distinct Immune Profiles of Exhausted Effector and Memory CD8+ T Cells in Individuals With Filarial Lymphedema
S Horn, D Borrero-Wolff, M Ritter, K Arndts… - Frontiers in Cellular …, 2021 - frontiersin.org
CD8+ T cells are crucial for the clearance of viral infections, and current research begins to
highlight their importance in parasitic diseases too. In-depth research about characteristics …
highlight their importance in parasitic diseases too. In-depth research about characteristics …
Contribution of the TIM-3/Gal-9 immune checkpoint to tropical parasitic diseases
C Bailly - Acta Tropica, 2023 - Elsevier
Neglected tropical parasitic diseases (NTD) are prevalent in many countries and cost-
effective treatments remain urgently needed. Novel approaches have been proposed to …
effective treatments remain urgently needed. Novel approaches have been proposed to …
[HTML][HTML] Filarial lymphedema patients are characterized by exhausted CD4+ T cells
S Horn, M Ritter, K Arndts, D Borrero-Wolff… - Frontiers in Cellular …, 2022 - frontiersin.org
Worldwide, more than 200 million people are infected with filariae which can cause severe
symptoms leading to reduced quality of life and contribute to disability-adjusted life years …
symptoms leading to reduced quality of life and contribute to disability-adjusted life years …
Filariasis research–from basic research to drug development and novel diagnostics, over a decade of research at the Institute for Medical Microbiology, Immunology …
Filariae are vector borne parasitic nematodes, endemic in tropical and subtropical regions
causing avoidable infections ranging from asymptomatic to stigmatizing and disfiguring …
causing avoidable infections ranging from asymptomatic to stigmatizing and disfiguring …
Hookworm infection associates with a vaginal Type 1/Type 2 immune signature and increased HPV load
MA Omondi, EH Kamassa, G Katawa… - Frontiers in …, 2022 - frontiersin.org
Helminth infection-driven changes to immunity in the female reproductive tract (FRT) is an
immune axis that is currently understudied but can have major implications for the control of …
immune axis that is currently understudied but can have major implications for the control of …