Heterogeneity of lipopolysaccharide as source of variability in bioassays and LPS-binding proteins as remedy

AC Fux, C Casonato Melo, S Michelini… - International Journal of …, 2023 - mdpi.com
Lipopolysaccharide (LPS), also referred to as endotoxin, is the major component of Gram-
negative bacteria's outer cell wall. It is one of the main types of pathogen-associated …

Design and Characterization of Neutral Linker‐Based Bis‐Intercalator via Computer Simulations: Balancing DNA Binding and Cellular Uptake

P Pant - Chemistry & Biodiversity, 2024 - Wiley Online Library
Bis‐intercalators refer to a class of chemical compounds known for their unique ability to
simultaneously intercalate, or insert, into DNA at two distinct sites. These molecules typically …

Flexible RNA aptamers as inhibitors of Bacillus anthracis ribosomal protein S8: Insights from molecular dynamics simulations

P Pant - Biophysical Chemistry, 2024 - Elsevier
Bacillus anthracis, the causative agent of anthrax, poses a substantial threat to public health
and national security, and is recognized as a potential bioweapon due to its capacity to form …

A peptide bond from the inter-lobe segment in the bilobal lactoferrin Acts as a preferred site for cleavage for serine proteases to generate the perfect C-lobe: Structure …

J Singh, A Maurya, PK Singh, V Viswanathan… - The Protein …, 2021 - Springer
C-lobe represents the C-terminal half of lactoferrin which is a bilobal 80 kDa iron binding
glycoprotein. The two lobes are designated as N-lobe (Ser1-Glu333) and C-lobe (Arg344 …

The mechanism of action of Lactoferrin-nucleoside diphosphate kinase complex in combating biofilm formation

J Sikarwar, J Singh, TP Singh… - Protein and Peptide …, 2022 - ingentaconnect.com
Background: The ESKAPE group of pathogens which comprise of multidrug resistant
bacteria, namely Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …

Recombinant Enterococcus faecium expressing porcine lactoferricin exerts bactericidal effects and protects against enterotoxigenic Escherichia coli in mice

Y Shao, X Wang, F Li, S Ma, J Li, J He, Y Jiang… - Process …, 2022 - Elsevier
Porcine lactoferricin functions as an antibacterial peptide as well as an antiviral, antifungal,
tumor-growth inhibiting, and immune-enhancing agent. Herein, the optimized and non …

CHANGES IN THE LACTOFERRIN CONCENTRATION AT DRYING OFF PERIOD

B Trajkovska, L Kochoski, G Dimitrovska… - Horizons-International …, 2021 - uklo.edu.mk
In the lactation cycle of dairy cows, the dry off is a critical period of rest for the udder, in order
to optimize milk production in the next lactation. Lactoferrin (LF) is an iron-binding protein …