Introduction Several studies have reported on the maternal age‐associated risks of
congenital anomalies. However, there is a paucity of studies with comprehensive review of …

Although collectively they are fairly common, birth defects receive limited attention as a
group of outcomes either clinically or from a public health perspective. This article provides …

The present and future live birth prevalence of Down syndrome (DS) is of practical
importance for planning services and prioritizing research to support people living with the …

Objectives. We investigated the relationship between race/ethnicity and 27 major birth
defects. Methods. We pooled data from 12 population-based birth defects surveillance …

Objective A novel algorithm to identify fetal microdeletion events in maternal plasma has
been developed and used in clinical laboratory‐based noninvasive prenatal testing. We …

An infection with the Zika virus (ZIKV) is usually mild, with nonspecific symptoms and most
often asymptomatic. However, because of its causal relationship with severe congenital …

Background Congenital microcephaly has been linked to maternal Zika virus infection.
However, ascertaining infants diagnosed with microcephaly can be challenging. Methods …

Importance Congenital cytomegalovirus (cCMV) has received far less clinical and public
health attention as a teratogenic infection than the Zika virus epidemic. However, cCMV may …

The mechanisms contributing to age-related deterioration of the female reproductive system
are complex, however aberrant protein homeostasis is a major contributor. We elucidated …

Objectives To examine racial/ethnic-specific survival of children with major birth defects in
the US. Study design We pooled data on live births delivered during 1999-2007 with any of …