Leveraging User-Friendly Network Approaches to Extract Knowledge From High-Throughput Omics Datasets

PIP Ramos, LWP Arge, NCB Lima, KF Fukutani… - Frontiers in …, 2019 - frontiersin.org
Recent technological advances for the acquisition of multi-omics data have allowed an
unprecedented understanding of the complex intricacies of biological systems. In parallel, a …

A feature selection technique for inference of graphs from their known topological properties: Revealing scale-free gene regulatory networks

FM Lopes, DC Martins Jr, J Barrera, RM Cesar Jr - Information Sciences, 2014 - Elsevier
An important problem in bioinformatics is the inference of gene regulatory networks (GRNs)
from expression profiles. In general, the main limitations faced by GRN inference methods …

Gene expression complex networks: synthesis, identification, and analysis

FM Lopes, RM Cesar Jr, LDF Costa - Journal of Computational …, 2011 - liebertpub.com
Thanks to recent advances in molecular biology, allied to an ever increasing amount of
experimental data, the functional state of thousands of genes can now be extracted …

Exploiting medical-expert knowledge via a novel memetic algorithm for the inference of gene regulatory networks

A Segura-Ortiz, J García-Nieto… - … on Computational Science, 2024 - Springer
This study introduces an innovative memetic algorithm for optimizing the consensus of well-
adapted techniques for the inference of gene regulation networks. Building on the …

Inference of gene regulatory networks by topological prior information and data integration

DC Martins Jr, FM Lopes, SS Ray - … in the Analysis and Modeling of …, 2016 - igi-global.com
Abstract The inference of Gene Regulatory Networks (GRNs) is a very challenging problem
which has attracted increasing attention since the development of high-throughput …

Structural identifiability in low-rank matrix factorization

E Fritzilas, M Milanič, S Rahmann, YA Rios-Solis - Algorithmica, 2010 - Springer
In many signal processing and data mining applications, we need to approximate a given
matrix Y with a low-rank product Y≈ AX. Both matrices A and X are to be determined, but we …

An iterative feature selection method for GRNs inference by exploring topological properties

FM Lopes, DC Martins-Jr, J Barrera… - arXiv preprint arXiv …, 2011 - arxiv.org
An important problem in bioinformatics is the inference of gene regulatory networks (GRN)
from temporal expression profiles. In general, the main limitations faced by GRN inference …

Structural identifiability in low-rank matrix factorization

E Fritzilas, YA Rios-Solis, S Rahmann - … 2008 Dalian, China, June 27-29 …, 2008 - Springer
In many signal processing and data mining applications, we need to approximate a given
matrix Y of “sensor measurements” over several experiments by a low-rank product Y≈ A· X …

Fault diagnosis of sensor networked complex structures: a virtual beam-like structure approach

H Wang - 2017 - theses.lib.polyu.edu.hk
Fault detection and localization techniques are among the prominent technical processes
involved in ensuring reliability. This is particularly true with regard to safety related …

[PDF][PDF] Bayesian methods for inferring gene regulatory networks and protein profiles from gene expression microarrays data

MS Castillo, MCC Pérez, IMT Luna, DB Navarro - ugr.es
6 Método BFE para el análisis de microarrays 91 6.1 Marco de trabajo Bayesiano...................
92 6.1. 1 Formulación del problema................ 93 6.1. 2 Modelo observacional y modelo …