Traditional herbal medicine: Therapeutic potential in rheumatoid arthritis

Y Wang, S Chen, K Du, C Liang, S Wang… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Rheumatoid arthritis (RA) is a chronic inflammatory
autoimmune disease influenced by diverse endogenous and exogenous factors. It is …

TLR4 signaling pathway modulators as potential therapeutics in inflammation and sepsis

NN Kuzmich, KV Sivak, VN Chubarev, YB Porozov… - Vaccines, 2017 - mdpi.com
Toll-Like Receptor 4 (TLR4) signal pathway plays an important role in initiating the innate
immune response and its activation by bacterial endotoxin is responsible for chronic and …

Natural products, alone or in combination with FDA-approved drugs, to treat COVID-19 and lung cancer

L Yang, Z Wang - Biomedicines, 2021 - mdpi.com
As a public health emergency of international concern, the highly contagious coronavirus
disease 2019 (COVID-19) pandemic has been identified as a severe threat to the lives of …

Natural products for the treatment of autoimmune arthritis: their mechanisms of action, targeted delivery, and interplay with the host microbiome

S Dudics, D Langan, RR Meka, SH Venkatesha… - International Journal of …, 2018 - mdpi.com
Rheumatoid arthritis (RA) is a chronic, debilitating illness characterized by painful swelling
of the joints, inflammation of the synovial lining of the joints, and damage to cartilage and …

Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment

JAR Salvador, AS Leal, AS Valdeira… - European Journal of …, 2017 - Elsevier
Natural pentacyclic triterpenoids (PTs) have been often reported to exhibit a wide range of
biological activities. Among them, the anticancer and anti-inflammatory activities are the …

[HTML][HTML] Emerging nanoformulation strategies for phytocompounds and applications from drug delivery to phototherapy to imaging

HS Han, SY Koo, KY Choi - Bioactive Materials, 2022 - Elsevier
Over thousands of years, natural bioactive compounds derived from plants (bioactive
phytocompounds, BPCs) have been used worldwide to address human health issues …

Celastrol treatment protects against acute ischemic stroke-induced brain injury by promoting an IL-33/ST2 axis-mediated microglia/macrophage M2 polarization

M Jiang, X Liu, D Zhang, Y Wang, X Hu, F Xu… - Journal of …, 2018 - Springer
Background Acute ischemic stroke (AIS) is the most common type of cerebrovascular
disease and is a leading cause of disability and death worldwide. Recently, a study …

Pathogenesis of rheumatoid arthritis and its treatment with anti-inflammatory natural products

A Sharma, A Goel - Molecular Biology Reports, 2023 - Springer
Introduction Rheumatoid arthritis (RA) is a common autoimmune disease across the globe
that is chronic and systemic as well. The disease is linked with autoantibodies and is …

[HTML][HTML] Dissolving microneedle patches-mediated percutaneous delivery of tetramethylpyrazine for rheumatoid arthritis treatment

W Zhao, L Zheng, J Yang, Y Li, Y Zhang, T Ma… - European Journal of …, 2023 - Elsevier
Recently, transdermal treatment of rheumatoid arthritis (RA) has received increasing
attention due to the advantages of improving patient compliance and avoiding …

Targeted delivery of celastrol to glomerular endothelium and podocytes for chronic kidney disease treatment

Q Wu, J Wang, Y Wang, L Xiang, Y Tan, J Feng… - Nano Research, 2022 - Springer
The etiology of chronic kidney disease (CKD) is complex and diverse, which could be briefly
categorized to glomerular-or tubular-originated. However, the final outcomes of CKD are …