Genetics factors in major depression disease

M Shadrina, EA Bondarenko, PA Slominsky - Frontiers in psychiatry, 2018 - frontiersin.org
Depressive disorders (DDs) are one of the most widespread forms of psychiatric pathology.
According to the World Health Organization, about 350 million people in the world are …

The neurobiology of human aggressive behavior: neuroimaging, genetic, and neurochemical aspects

FA Cupaioli, FA Zucca, C Caporale, KP Lesch… - Progress in neuro …, 2021 - Elsevier
In modern societies, there is a strive to improve the quality of life related to risk of crimes
which inevitably requires a better understanding of brain determinants and mediators of …

Genes, economics, and happiness.

JE De Neve, NA Christakis, JH Fowler… - Journal of neuroscience …, 2012 - psycnet.apa.org
We explore the influence of genetic variation on subjective well-being by employing a twin
design and genetic association study. In a nationally representative twin sample, we first …

The neurobiological basis of suicide

Y Dwivedi - 2012 - books.google.com
With recent studies using genetic, epigenetic, and other molecular and neurochemical
approaches, a new era has begun in understanding pathophysiology of suicide. Emerging …

The other allele: Exploring the long allele of the serotonin transporter gene as a potential risk factor for psychopathy: A review of the parallels in findings

AL Glenn - Neuroscience & Biobehavioral Reviews, 2011 - Elsevier
Converging evidence suggests that the short allele of the serotonin transporter gene
polymorphism increases risk for a variety of psychological disorders, including depression …

Role of the 5-HTTLPR and SNP promoter polymorphisms on serotonin transporter gene expression: a closer look at genetic architecture and in vitro functional studies …

S Iurescia, D Seripa, M Rinaldi - Molecular neurobiology, 2016 - Springer
Abstract The serotonin (5-hydroxytriptamine (5-HT)) transporter (5-HTT) gene-linked
polymorphic region (5-HTTLPR) is a variable number tandem repeats (VNTR) located in the …

Human serotonin transporter gene (SLC6A4) variants: their contributions to understanding pharmacogenomic and other functional G× G and G× E differences in …

DL Murphy, PR Moya - Current opinion in pharmacology, 2011 - Elsevier
Recent major findings from studies of SLC6A4 and its corresponding protein, the serotonin
(5-HT) transporter (SERT) in humans, rodents and non-human primates indicate that …

Multifaceted regulations of the serotonin transporter: impact on antidepressant response

A Baudry, M Pietri, JM Launay, O Kellermann… - Frontiers in …, 2019 - frontiersin.org
Serotonin transporter, SERT (SLC64A for solute carrier family 6, member A4), is a twelve
transmembrane domain (TMDs) protein that assumes the uptake of serotonin (5-HT) through …

Characterisation of the potential function of SVA retrotransposons to modulate gene expression patterns

AL Savage, VJ Bubb, G Breen, JP Quinn - BMC evolutionary biology, 2013 - Springer
Background Retrotransposons are a major component of the human genome constituting as
much as 45%. The hominid specific SINE-VNTR-Alus are the youngest of these elements …

11 Genetic Factors and Suicidal Behavior

CC Zai, V de Luca, J Strauss, RP Tong… - … basis of suicide, 2012 - books.google.com
Approximately 1 million people worldwide die by suicide each year. With a prevalence rate
of 0.0145% and suicide accounting for 1.5% of death by all causes, it is the 10th leading …