[HTML][HTML] Role of plant-derived compounds in the molecular pathways related to inflammation

AJ Olędzka, ME Czerwińska - International Journal of Molecular Sciences, 2023 - mdpi.com
Inflammation is the primary response to infection and injury. Its beneficial effect is an
immediate resolution of the pathophysiological event. However, sustained production of …

[HTML][HTML] Preparation, physicochemical characterization, and bioactivity evaluation of berberine-entrapped albumin nanoparticles

FA Younis, SR Saleh, SSA El-Rahman… - Scientific Reports, 2022 - nature.com
Berberine (BBR) is an isoquinoline alkaloid with several clinical therapeutic applications. Its
low water solubility, absorption, and cellular bioavailability diminish BBR's therapeutic …

In vivo, in vitro and in silico anticancer investigation of fullerene C60 on DMBA induced breast cancer in rats

S Beyaz, A Aslan, O Gok, H Uslu, CA Agca, IH Ozercan - Life sciences, 2022 - Elsevier
Aims The aim of the study was to determine the protective and therapeutic effect of fullerene
C 60 nanoparticle on DMBA-induced breast cancer in rats. Main methods In vitro cell …

Royal jelly abrogates flouride-induced oxidative damage in rat heart tissue by activating of the nrf-2/NF-κB and bcl-2/bax pathway

A Aslan, S Beyaz, O Gok, MI Can, G Parlak… - Toxicology …, 2021 - Taylor & Francis
Royal jelly is known to strengthen memory, provide antioxidative, antidiabetic, antitumor,
anticancer, antibacterial, antiinflammatory, antihypertensive. In this study, 42 rats (n= 42) …

Royal jelly regulates the caspase, Bax and COX-2, TNF-α protein pathways in the fluoride exposed lung damage in rats

A Aslan, O Gok, S Beyaz, MI Can, G Parlak… - Tissue and Cell, 2022 - Elsevier
The study was carried out on 42 male rats divided into six groups with 7 rats in each group:
two control groups, two injury groups and two treatment groups. One of the control groups …

Royal jelly protects brain tissue against fluoride-induced damage by activating Bcl-2/NF-κB/caspase-3/caspase-6/Bax and Erk signaling pathways in rats

A Aslan, S Beyaz, O Gok, G Parlak, MI Can… - … Science and Pollution …, 2023 - Springer
This study is aimed at determining whether royal jelly (RJ) which has a powerful antioxidant
property prevents fluoride-induced brain tissue damage and exploring whether Bcl-2/NF …

Fullerene C60 protects against 7,12-dimethylbenz [a] anthracene (DMBA) induced-pancreatic damage via NF-κB and Nrf-2/HO-1 axis in rats

S Beyaz, A Aslan, O Gok, IH Ozercan… - Toxicology …, 2023 - academic.oup.com
The objective of this investigation was to investigate the protective effects of fullerene C60
nanoparticle against pancreatic damage experimentally induced by 7, 12-dimethylbenz [a] …

Royal jelly arranges apoptotic and oxidative stress pathways and reduces damage to liver tissues of rats by down-regulation of Bcl-2, GSK3 and NF-κB and up …

A Aslan, O Gok, S Beyaz, G Parlak, MI Can… - Biomarkers, 2023 - Taylor & Francis
Introduction Royal jelly (RJ) from the honey bee, Apis mellifera, is a traditional product that is
widely used as a food supplement to support the medical treatment of various diseases …

C60 Nanoparticle Decrease the Inflammatory and Oxidative Responses in 7,12-Dimethylbenz[a]Anthracene (DMBA) Induced Rats Eye Tissue

S Beyaz, A Aslan, O Gok, IH Ozercan, CA Agca - Biology Bulletin, 2023 - Springer
Fullerene C60 is known to have particularly strong antioxidant ability to protect against
oxidative stress-induced dysfunctions and tissue damage. In this study, the preventive …

[HTML][HTML] The research progress of anti-inflammatory and anti-fibrosis treatment of chronic pancreatitis

BQ Li, XY Liu, T Mao, TH Zheng, P Zhang… - Frontiers in …, 2022 - frontiersin.org
Chronic pancreatitis (CP) is a chronic progressive inflammatory disease of the pancreas,
caused by multiple factors and accompanied by irreversible impairment of pancreatic …