The present review is an update of the research and development efforts regarding the use
of molecular biomarkers in the lung cancer screening setting. The two main unmet clinical …

The known genetic architecture of blood pressure now comprises> 30 genes, with rare
variants resulting in monogenic forms of hypertension or hypotension and> 1,477 common …

People differ in their requirements for and responses to nutrients and bioactive molecules in
the diet. Many inputs contribute to metabolic heterogeneity (including variations in genetics …

While genetic testing may be the gateway to the future of medicine, it also poses challenges
for individuals, especially in terms of differentiated treatments on the basis of their genetic …

The genetic architecture of blood pressure (BP) now includes more than 30 genes, with rare
mutations resulting in inherited forms of hypertension or hypotension, and 1477 common …

This study investigates changes in the social valuation of the human genome over the more
than 30 years since the establishment of the Human Genome Project. It offers a descriptive …

Genetic testing for cancer predisposition has been curtailed by the cost of sequencing, and
testing has been restricted by eligibility criteria. As the cost of sequencing decreases, the …

Governments are investing in precision medicine (PM) with the aim of improving healthcare
through the use of genomic analyses and data analytics to develop tailored treatment …

Despite longstanding attempts to conceptualise and measure value in biomedicine and
healthcare, there is no single agreed definition of what value is. Instead, and as such, value …

Personalized healthcare (PHC) based on an individual's genetic make-up is one of the most
advanced, yet feasible, forms of medical care. The Tohoku Medical Megabank (TMM) …