Asthma is a common disease affecting 350 million people worldwide, which is characterized
by airways inflammation and hyperreactivity. Historically diagnosis and treatment have been …

Asthma is a chronic inflammatory disease of the airways, affecting over 350 million people
worldwide and placing a significant burden on healthcare providers and wider society …

Glucocorticosteroids are the first-line therapy for controlling airway inflammation in asthma.
They bind intracellular glucocorticoid receptors to trigger increased expression of anti …

Medication non-adherence to asthma and chronic obstructive pulmonary disease therapy
poses a significant burden for patients and societies. Non-adherence encompasses poor …

Background Clinical trials with mepolizumab, a humanised monoclonal antibody against
interleukin-5, show a 50% reduction in severe asthma exacerbations in people with severe …

Coronavirus disease 2019 (COVID-19), an illness caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection, has spread rapidly worldwide, resulting in …

The identification of sputum eosinophilia indicating corticosteroid responsiveness in
subjects with severe asthma heralded the beginning of phenotyping asthmatic subjects …

Fractional Exhaled Nitric Oxide Nonsuppression Identifies Corticosteroid-Resistant Type 2
Signaling in Severe Asthma | American Journal of Respiratory and Critical Care Medicine ATS …

The detection of chemical compounds in exhaled human breath presents an opportunity to
determine physiological state, diagnose disease or assess environmental exposure. Recent …

Asthma is a heterogenous disorder characterized by presence of different phenotypes and
endotypes. Up to 10% of the individuals suffer from severe asthma and are at increased risk …