Bioactive natural products in COVID-19 therapy

Z Wang, N Wang, L Yang, X Song - Frontiers in Pharmacology, 2022 - frontiersin.org
The devastating COVID-19 pandemic has caused more than six million deaths worldwide
during the last 2 years. Effective therapeutic agents are greatly needed, yet promising magic …

Bioactives from marine resources as natural health products: A review

S Santhiravel, D Dave, F Shahidi - Pharmacological Reviews, 2024 - Elsevier
The oceans are a rich source of a myriad of structurally different and unique natural products
that are mainly found in invertebrates with potential applications in different disciplines …

Identification of novel inhibitors for SARS-CoV-2 as therapeutic options using machine learning-based virtual screening, molecular docking and MD simulation

A Samad, A Ajmal, A Mahmood, B Khurshid… - Frontiers in Molecular …, 2023 - frontiersin.org
The new coronavirus SARS-COV-2, which emerged in late 2019 from Wuhan city of China
was regarded as causing agent of the COVID-19 pandemic. The primary protease which is …

Integrated bioinformatics–cheminformatics approach toward locating pseudo‐potential antiviral marine alkaloids against SARS‐CoV‐2‐Mpro

SS Swain, SR Singh, A Sahoo… - Proteins: Structure …, 2022 - Wiley Online Library
The emergence of the severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2)
with the most contagious variants, alpha (B. 1.1. 7), beta (B. 1.351), delta (B. 1.617. 2), and …

Ethnomedicinal, Phytochemical and Pharmacological Investigations of Tetradenia riparia (Hochst.) Codd (Lamiaceae)

SK Panda, ZC Gazim, SS Swain… - Frontiers in …, 2022 - frontiersin.org
Tetradenia riparia Hochsteter codd.(Lamiaceae) in its native African continent, is considered
one of the most popular aromatic medicinal plants. In folk medicine it may be used as an …

Plants as biofactories for therapeutic proteins and antiviral compounds to combat COVID-19

C England, J TrejoMartinez, P PerezSanchez, U Karki… - Life, 2023 - mdpi.com
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) had a profound impact on the world's health and …

Combined Bioinformatics and Combinatorial Chemistry Tools to Locate Drug‐Able Anti‐TB Phytochemicals: A Cost‐Effective Platform for Natural Product‐Based Drug …

SS Swain, T Hussain - Chemistry & Biodiversity, 2022 - Wiley Online Library
Based on extensive experimental studies, a huge number of phytochemicals showed
potential activity against tuberculosis (TB) at a lower minimum inhibitory concentration (MIC) …

Multimodal antibacterial potency of newly designed and synthesized Schiff's/Mannich based coumarin derivatives: potential inhibitors of bacterial DNA gyrase and …

K Pakeeraiah, PP Swain, A Sahoo, PK Panda… - RSC …, 2024 - pubs.rsc.org
The briskened urge to develop potential antibacterial candidates against multidrug-resistant
pathogens has motivated the present research study. Herein, newly synthesized coumarin …

In Silico Identification of Potential Insect Peptides against Biofilm‐Producing Staphylococcus aureus

A Sahoo, SS Swain, SK Panda, T Hussain… - Chemistry & …, 2022 - Wiley Online Library
Biofilm‐producing Staphylococcus aureus (SA) strains are frequently found in medical
environments, from surgical/wound sites, medical devices. These biofilms reduce the …

Synthesis, α-glucosidase inhibitory activity, and molecular docking of cinnamamides

NP Aijijiyah, FA Wati, R Rahayu, A Srilistiani… - Medicinal Chemistry …, 2023 - Springer
Suitably substituted cinnamamides (3a-n) were successfully synthesized and tested for α-
glucosidase inhibitory activity. Nine of the synthesized cinnamamides (3a-f, km) displayed …