This report on vitamin B-12 (B12) is part of the Biomarkers of Nutrition for Development
(BOND) Project, which provides state-of-the art information and advice on the selection, use …

Hyperhomocysteinemia/Homocysteinuria is characterized by an increased level of toxic
homocysteine in the plasma. The plasma concentration of homocysteine is 5–15 μmol/L in …

Within the last few years, knowledge about vitamins has increased dramatically. This new
edition of a bestseller presents comprehensive summaries that analyze the chemical …

Tetrahydrofolate (THF) polyglutamates are a family of cofactors that carry and chemically
activate one‐carbon units for biosynthesis. THF‐mediated one‐carbon metabolism is a …

During the fifteen years since the bestselling first edition of Folate in Health and Disease
was published, there have been thousands of new research studies related to folate and its …

Craniofacial development involves several complex tissue movements including several
fusion processes to form the frontonasal and maxillary structures, including the upper lip and …

Background The ability of folic acid in the periconceptional period to prevent the occurrence
of neural tube defects has stimulated tremendous interest in its effects on other health …

Nonsyndromic cleft lip and/or palate (or orofacial cleft, OFC) is a malformation characterized
by an incomplete separation between nasal and oral cavities without any associated …

Dental caries is the most common chronic disease in children and a major public health
concern due to its increasing incidence, serious health and social co-morbidities, and socio …

Nonsyndromic orofacial clefts are a common complex birth defect caused by genetic and
environmental factors and/or their interactions. A previous genome-wide linkage scan …