Despite known drawbacks, rodent models are essential tools in the research of renal
development, physiology, and pathogenesis. In the past decade, rodent models have been …

Biomaterials encounter considerable challenges in extensive bone defect regeneration. The
amelioration of outcomes may be attainable through the orchestrated modulation of both …

Dysregulation of the gut microbial ecosystem (GME)(eg, alterations in the gut microbiota, gut-
derived metabolites, and gut barrier) may contribute to the onset and progression of extra …

As a novel type of nanomaterials, black phosphorus quantum dots (BPQDs) have wide
application potential, including anti-pathogenic bacteria. However, there is no information on …

In this study, we sought to evaluate the influence of positive pathogens in stool (PPS) on
clinical outcomes in critical ill patients with Sepsis-associated acute kidney injury (S-AKI) …

Intestinal microbiota and their metabolites affect systemic inflammation and kidney disease
outcomes. Here, we investigated the key metabolites associated with the acute kidney injury …

The microbiota plays important roles in the health and diseases of its host. Gharaie et al.
demonstrated that antibiotic treatment, especially amoxicillin, facilitated the repair process …

Multiple types of T cells have been described and assigned pathophysiologic functions in
the kidneys. However, the existence and functions of TCR+ CD4+ CD8+ (double positive; …

Background Acute kidney injury (AKI) is a serious clinical emergency with an acute onset,
rapid progression and poor prognosis, which has high morbidity and mortality in …

Acute kidney injury (AKI) is a critical condition often associated with systemic inflammation
and dysregulated gut microbiota. This study aimed to investigate the effects of the C5a …