Despite recent advances in the management of chronic kidney disease (CKD), morbidity
and mortality rates in these patients remain high. While pressure-mediated injury is a well …

The plasma compartment has particular features regarding the nature and concentration of
low and high molecular weight thiols and oxidized derivatives. Plasma is relatively poor in …

Background: Urinary excretion of albumin indicates kidney damage and is recognized as a
risk factor for progression of kidney disease and cardiovascular disease. The role of urinary …

Background Oxidative damage results in protein modification, and is observed in numerous
diseases. Human serum albumin (HSA), the most abundant circulating protein in the …

The degree of oxidized cysteine (Cys) 34 in human serum albumin (HSA), as determined by
high performance liquid chromatography (HPLC), is correlated with oxidative stress related …

Significance: Albumin is the major contributor to colloid oncotic pressure and also serves as
an important carrier protein of many endogenous and exogenous molecules throughout the …

During the proteomic era, one of the most rapidly growing areas in biomedical research is
biomarker discovery, particularly using proteomic technologies. Urinary proteomics has …

It is currently postulated that steroid-sensitive idiopathic nephrotic syndrome (SSNS) and
steroid-resistant idiopathic nephrotic syndrome (SRNS), which are not related to the …

Since the first demonstration of Nox enzyme expression in the kidney in the early 1990s and
the subsequent identification of Nox4, or RENOX, a decade later, it has become apparent …

Recent research findings indicate that the posttranslational modification of human serum
albumin (HSA) such as oxidation, glycation, truncation, dimerization, and carbamylation is …