Applications of focused ultrasound-mediated blood-brain barrier opening

CM Gorick, VR Breza, KM Nowak, VWT Cheng… - Advanced drug delivery …, 2022 - Elsevier
The blood brain barrier (BBB) plays a critically important role in the regulation of central
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …

[HTML][HTML] Ultrasound-responsive cavitation nuclei for therapy and drug delivery

K Kooiman, S Roovers, SAG Langeveld… - Ultrasound in medicine …, 2020 - Elsevier
Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …

Clinical intervention using focused ultrasound (FUS) stimulation of the brain in diverse neurological disorders

H Baek, D Lockwood, EJ Mason, E Obusez… - Frontiers in …, 2022 - frontiersin.org
Various surgical techniques and pharmaceutical treatments have been developed to
improve the current technologies of treating brain diseases. Focused ultrasound (FUS) is a …

Ultrasound for the brain: a review of physical and engineering principles, and clinical applications

W Qiu, A Bouakaz, EE Konofagou… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
The emergence of new ultrasound technologies has improved our understanding of the
brain functions and offered new opportunities for the treatment of brain diseases. Ultrasound …

Recent advances of focused ultrasound induced blood-brain barrier opening for clinical applications of neurodegenerative diseases

P Zhao, T Wu, Y Tian, J You, X Cui - Advanced Drug Delivery Reviews, 2024 - Elsevier
With the aging population on the rise, neurodegenerative disorders have taken center stage
as a significant health concern. The blood–brain barrier (BBB) plays an important role to …

An efficient method for transcranial ultrasound focus correction based on the coupling of boundary integrals and finite elements

F Shen, F Fan, F Li, L Wang, R Wang, Y Wang, T Liu… - Ultrasonics, 2024 - Elsevier
Transcranial focused ultrasound is a novel technique for the noninvasive treatment of brain
diseases. The success of the treatment greatly depends on achieving precise and efficient …

A dual-mode 2D matrix array for ultrasound image-guided noninvasive therapy

Z Zhang, R Liu, G Li, M Su, F Li… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
Focused ultrasound (FUS) lacks reliable real-time image guidance, which hinders the
development of non-invasive ultrasound treatment in many important clinical applications. A …

Focused ultrasound: growth potential and future directions in neurosurgery

M Zhang, A Rodrigues, Q Zhou, G Li - Journal of Neuro-Oncology, 2022 - Springer
Over the past two decades, vast improvements in focused ultrasound (FUS) technology have
made the therapy an exciting addition to the neurosurgical armamentarium. In this time …

[HTML][HTML] Noninvasive low-intensity focused ultrasound mediates tissue protection following ischemic stroke

M KalossAlexandra, N ArnoldLauren… - BME …, 2022 - spj.science.org
Abstract Objective and Impact Statement. This study examined the efficacy and safety of
pulsed, low-intensity focused ultrasound (LIFU) and determined its ability to provide …

[HTML][HTML] Therapeutic applications of ultrasound in neurological diseases

KH Choi, JH Kim - Journal of Neurosonology and Neuroimaging, 2019 - j-nn.org
Ultrasonography is well recognized as an imaging tool. Recent research in the therapeutic
applications of ultrasound has made great progress. Ultrasound can be widely used in …