Combination antibiotic therapy for invasive infections with Gram-negative bacteria is
employed in many health care facilities, especially for certain subgroups of patients …

Infections caused by multi-resistant Gram-negative bacteria, particularly Pseudomonas
aeruginosa, are increasing worldwide. In patients with cystic fibrosis (CF), resistance in P …

Bacteria have the potential to translocate between sites in the human body, but the
dynamics and consequences of within-host bacterial migration remain poorly understood …

The rise of antibiotic resistance in many bacterial pathogens has been driven by the spread
of a few successful strains, suggesting that some bacteria are genetically pre-disposed to …

Objectives We conducted a systematic review and meta-analysis to summarize the clinical
evidence and usage patterns of intravenous fosfomycin from its development to the present …

Severe sepsis and septic shock are as common and lethal as other acute life-threatening
conditions that emergency physicians routinely confront such as acute myocardial infarction …

Isolates of Pseudomonas aeruginosa or Acinetobacter species that are resistant to all, or
almost all, commercially available antibiotics are now prevalent worldwide. Typically, these …

The use of combination antimicrobial therapy for bacteraemia caused by Gram-negative
bacilli is controversial. We did a meta-analysis of published studies to determine whether a …

The selection of bacterial resistance was examined in relationship to antibiotic
pharmacokinetics (PK) and organism MICs in the patients from four nosocomial lower …

Antimicrobial agents are used in food animals for therapy and prophylaxis of bacterial
infections and in feed to promote growth. The use of antimicrobial agents for food animals …