The medicinal chemistry of ferrocene and its derivatives

M Patra, G Gasser - Nature Reviews Chemistry, 2017 - nature.com
Ferrocene derivatives have attracted significant interest as anticancer, antibacterial,
antifungal and antiparasitic drug candidates. Discovered in the 1990s, the two most …

Has ferrocene really delivered its role in accentuating the bioactivity of organic scaffolds?

B Sharma, V Kumar - Journal of medicinal chemistry, 2021 - ACS Publications
Ferrocene is an important structural core in bioorganometallic chemistry because of its
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …

Tamoxifen a pioneering drug: An update on the therapeutic potential of tamoxifen derivatives

I Ahmad - European journal of medicinal chemistry, 2018 - Elsevier
Abstract Tamoxifen (ICI 46 474), trans-1-(4-β-dimethylaminoethoxyphenyl)-1, 2-diphenylbut-
1-ene, is the most commonly used drug for the treatment of estrogen receptor positive breast …

Ferrocene-based drugs, delivery nanomaterials and fenton mechanism: state of the art, recent developments and prospects

C Ornelas, D Astruc - Pharmaceutics, 2023 - mdpi.com
Ferrocene has been the most used organometallic moiety introduced in organic and
bioinorganic drugs to cure cancers and various other diseases. Following several …

An overview of advancement of organoruthenium (II) complexes as prospective anticancer agents

M Bashir, IA Mantoo, F Arjmand, S Tabassum… - Coordination Chemistry …, 2023 - Elsevier
The successful clinical translation of platinum drugs for cancer treatment has witnessed an
upsurge in the development of metal compounds as therapeutics and diagnostics drugs …

On the medicinal chemistry of ferrocene

MFR Fouda, MM Abd‐Elzaher… - Applied …, 2007 - Wiley Online Library
Organometallic chemistry and biochemistry have been merged in the last two decades into a
new field: bioorganometallic chemistry. This new research area was devoted to the …

The truncated wigner method for bose-condensed gases: limits of validity and applications1

A Sinatra, C Lobo, Y Castin - … of Physics B: Atomic, Molecular and …, 2002 - iopscience.iop.org
We study the truncated Wigner method applied to a weakly interacting spinless Bose-
condensed gas which is perturbed away from thermal equilibrium by a time-dependent …

Recent advances in the synthesis, biological activities and various applications of ferrocene derivatives

FA Larik, A Saeed, TA Fattah… - Applied …, 2017 - Wiley Online Library
Ferrocene derivatives constitute an important class of organometallic compounds with not
only an extensive range of biological activities but also diverse industrial as well as material …

Exploring biologically relevant chemical space with metal complexes

E Meggers - Current opinion in chemical biology, 2007 - Elsevier
Altering biological processes with small synthetic molecules is a general approach for the
design of drugs and molecular probes. Medicinal chemistry and chemical biology are …

On the discovery, biological effects, and use of cisplatin and metallocenes in anticancer chemotherapy

S Gomez-Ruiz, D Maksimović-Ivanić… - Bioinorganic …, 2012 - Wiley Online Library
The purpose of this paper is to summarize mode of action of cisplatin on the tumor cells, a
brief outlook on the metallocene compounds as antitumor drugs as well as the future …