Genetic studies show that Msx2 and Dlx5 homeodomain (HD) proteins support skeletal
development, but null mutation of the closely related Dlx3 gene results in early embryonic …

This article describes several recent examples of miRNA governing the regulation of the
gene expression involved in bone matrix construction. We present the impact of miRNA on …

Our laboratory and others have shown that overexpression of Dlx5 stimulates osteoblast
differentiation. Dlx5−/−/Dlx6−/− mice have more severe craniofacial and limb defects than …

During the phase of overt tooth cytodifferentiation that occurs after birth in the mouse and
using the 3.6 Collagen1a-Cre and the BMP4 floxed and BMP4 knockout mice, the BMP4 …

Commercially‐pure titanium (cp‐Ti) and the titanium‐aluminum‐vanadium alloy (Ti6Al4V)
are widely used as reconstructive implants for skeletal engineering applications, due to their …

The process of endochondral ossification in which the bones of the limb are formed after
generation of cartilage models is dependent on a precisely regulated program of …

Tooth development is a complex process including successive stages of initiation,
morphogenesis, and histogenesis. The role of the Dlx family of homeobox genes during the …

Myeloid Elf‐1 like factor (MEF) is a member of the Ets transcription factor family. Ets family
proteins control the expression of genes that are critical for biological processes such as …

Aim. To study the effect of Dlx5 introduced by replication-competent avian splice-acceptor
(RCAS) in mouse calvarial and bone marrow stromal cells, and to demonstrate that RCAS …

Dlx5 transcription factor plays important roles in osteoblast differentiation and its
transcription is regulated by many osteogenic signals including BMP-2. Recent studies …