[HTML][HTML] Hypoxia, partial EMT and collective migration: Emerging culprits in metastasis
Epithelial-mesenchymal transition (EMT) is a cellular biological process involved in
migration of primary cancer cells to secondary sites facilitating metastasis. Besides, EMT …
migration of primary cancer cells to secondary sites facilitating metastasis. Besides, EMT …
[HTML][HTML] Epigenetic and breast cancer therapy: promising diagnostic and therapeutic applications
The global burden of breast cancer (BC) is increasing significantly. This trend is caused by
several factors such as late diagnosis, limited treatment options for certain BC subtypes …
several factors such as late diagnosis, limited treatment options for certain BC subtypes …
Zinc-dependent regulation of ZEB1 and YAP1 coactivation promotes epithelial-mesenchymal transition plasticity and metastasis in pancreatic cancer
Background Pancreatic cancer is characterized by extensive metastasis. Epithelial-
mesenchymal transition (EMT) plasticity plays a critical role in tumor progression and …
mesenchymal transition (EMT) plasticity plays a critical role in tumor progression and …
Comparative study of transcriptomics-based scoring metrics for the epithelial-hybrid-mesenchymal spectrum
The Epithelial–mesenchymal transition (EMT) is a cellular process implicated in embryonic
development, wound healing, and pathological conditions such as cancer metastasis and …
development, wound healing, and pathological conditions such as cancer metastasis and …
Epigenetic regulation of hybrid epithelial-mesenchymal cell states in cancer
RA Sample, MF Nogueira, RD Mitra, SV Puram - Oncogene, 2023 - nature.com
Epithelial-to-mesenchymal transition (EMT) is a process by which cells lose their epithelial
characteristics and gain mesenchymal phenotypes. In cancer, EMT is thought to drive tumor …
characteristics and gain mesenchymal phenotypes. In cancer, EMT is thought to drive tumor …
Targeting chromatin-remodeling factors in cancer cells: promising molecules in cancer therapy
FL Zhang, DQ Li - International Journal of Molecular Sciences, 2022 - mdpi.com
ATP-dependent chromatin-remodeling complexes can reorganize and remodel chromatin
and thereby act as important regulator in various cellular processes. Based on considerable …
and thereby act as important regulator in various cellular processes. Based on considerable …
Emerging roles of endoplasmic reticulum stress in the cellular plasticity of cancer cells
H Wang, K Mi - Frontiers in Oncology, 2023 - frontiersin.org
Cellular plasticity is a well-known dynamic feature of tumor cells that endows tumors with
heterogeneity and therapeutic resistance and alters their invasion–metastasis progression …
heterogeneity and therapeutic resistance and alters their invasion–metastasis progression …
MBD3 promotes hepatocellular carcinoma progression and metastasis through negative regulation of tumour suppressor TFPI2
W Yan, Q Han, L Gong, X Zhan, W Li, Z Guo… - British Journal of …, 2022 - nature.com
Background The mechanism of recurrence and metastasis of hepatocellular carcinoma
(HCC) is complex and challenging. Methyl-CpG binding domain protein 3 (MBD3) is a key …
(HCC) is complex and challenging. Methyl-CpG binding domain protein 3 (MBD3) is a key …
[HTML][HTML] Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT
Epithelial-mesenchymal transition (EMT) and its reverse process mesenchymal-epithelial
transition (MET) are central to metastatic aggressiveness and therapy resistance in solid …
transition (MET) are central to metastatic aggressiveness and therapy resistance in solid …
[HTML][HTML] Factors determining epithelial-mesenchymal transition in cancer progression
P Tomecka, D Kunachowicz, J Górczyńska… - International Journal of …, 2024 - mdpi.com
Epithelial-mesenchymal transition (EMT) is a process in which an epithelial cell undergoes
multiple modifications, acquiring both morphological and functional characteristics of a …
multiple modifications, acquiring both morphological and functional characteristics of a …