The primate fovea: structure, function and development
A Bringmann, S Syrbe, K Görner, J Kacza… - Progress in retinal and …, 2018 - Elsevier
A fovea is a pitted invagination in the inner retinal tissue (fovea interna) that overlies an area
of photoreceptors specialized for high acuity vision (fovea externa). Although the shape of …
of photoreceptors specialized for high acuity vision (fovea externa). Although the shape of …
[HTML][HTML] Fgf8 expression and degradation of retinoic acid are required for patterning a high-acuity area in the retina
S da Silva, CL Cepko - Developmental cell, 2017 - cell.com
Species that are highly reliant on their visual system have a specialized retinal area
subserving high-acuity vision, eg, the fovea in humans. Although of critical importance for …
subserving high-acuity vision, eg, the fovea in humans. Although of critical importance for …
[HTML][HTML] Microfluidic and microscale assays to examine regenerative strategies in the neuro retina
M Vazquez - Micromachines, 2020 - mdpi.com
Bioengineering systems have transformed scientific knowledge of cellular behaviors in the
nervous system (NS) and pioneered innovative, regenerative therapies to treat adult neural …
nervous system (NS) and pioneered innovative, regenerative therapies to treat adult neural …
Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye
G Alfano, I Conte, T Caramico, R Avellino… - …, 2011 - journals.biologists.com
Vax2 is an eye-specific homeobox gene, the inactivation of which in mouse leads to
alterations in the establishment of a proper dorsoventral eye axis during embryonic …
alterations in the establishment of a proper dorsoventral eye axis during embryonic …
Role of bone morphogenic protein 2 in retinal patterning and retinotectal projection
H Sakuta, H Takahashi, T Shintani, K Etani… - Journal of …, 2006 - Soc Neuroscience
It has been long believed that the anteroposterior (AP) and dorsoventral (DV) axes in the
developing retina are determined independently and also that the retinotectal projection …
developing retina are determined independently and also that the retinotectal projection …
[HTML][HTML] Genetic Dissection of Dual Roles for the Transcription Factor six7 in Photoreceptor Development and Patterning in Zebrafish
M Sotolongo-Lopez, K Alvarez-Delfin, CJ Saade… - PLoS …, 2016 - journals.plos.org
The visual system of a particular species is highly adapted to convey detailed ecological and
behavioral information essential for survival. The consequences of structural mutations of …
behavioral information essential for survival. The consequences of structural mutations of …
[HTML][HTML] Anteroventrally localized activity in the optic vesicle plays a crucial role in the optic development
M Hirashima, T Kobayashi, M Uchikawa, H Kondoh… - Developmental …, 2008 - Elsevier
The vertebrate eye develops from the optic vesicle (OV), a laterally protrusive structure of the
forebrain, by a coordinated interaction with surrounding tissues. The OV then invaginates to …
forebrain, by a coordinated interaction with surrounding tissues. The OV then invaginates to …
[HTML][HTML] Central and peripheral retina arise through distinct developmental paths
SJ Venters, T Mikawa, J Hyer - PloS one, 2013 - journals.plos.org
In the mature eye, three distinct tissue fates, retina, ciliary body, and iris, arrange with a strict
linear organization along the central (back) to peripheral (front) axis. The establishment of …
linear organization along the central (back) to peripheral (front) axis. The establishment of …
Molecular mechanisms of vertebrate retina development: implications for ganglion cell and photoreceptor patterning
D Schulte, KM Bumsted-O'Brien - Brain research, 2008 - Elsevier
Although the neural retina appears as a relatively uniform tissue when viewed from its
surface, it is in fact highly patterned along its anterior–posterior and dorso-ventral axes. The …
surface, it is in fact highly patterned along its anterior–posterior and dorso-ventral axes. The …
Early divergence of central and peripheral neural retina precursors during vertebrate eye development
SJ Venters, T Mikawa, J Hyer - Developmental Dynamics, 2015 - Wiley Online Library
Background: During development of the vertebrate eye, optic tissue is progressively
compartmentalized into functionally distinct tissues. From the central to the peripheral optic …
compartmentalized into functionally distinct tissues. From the central to the peripheral optic …