Close-to-native bone repair via tissue-engineered endochondral ossification approaches
In order to solve the clinical challenges related to bone grafting, several tissue engineering
(TE) strategies have been proposed to repair critical-sized defects. Generally, the classical …
(TE) strategies have been proposed to repair critical-sized defects. Generally, the classical …
Bioengineered living bone grafts—A concise review on bioreactors and production techniques in vitro
P Kazimierczak, A Przekora - International journal of molecular sciences, 2022 - mdpi.com
It has been observed that bone fractures carry a risk of high mortality and morbidity. The
deployment of a proper bone healing method is essential to achieve the desired success …
deployment of a proper bone healing method is essential to achieve the desired success …
A 3D printed polylactic acid-Baghdadite nanocomposite scaffold coated with microporous chitosan-VEGF for bone regeneration applications
Abstract Three-dimensional (3D) printing technology has become an advanced approach for
fabricating patient-specific scaffolds with complex geometric shapes to replace damaged or …
fabricating patient-specific scaffolds with complex geometric shapes to replace damaged or …
The role of HIF-1α in bone regeneration: a new direction and challenge in bone tissue engineering
J You, M Liu, M Li, S Zhai, S Quni, L Zhang… - International Journal of …, 2023 - mdpi.com
The process of repairing significant bone defects requires the recruitment of a considerable
number of cells for osteogenesis-related activities, which implies the consumption of a …
number of cells for osteogenesis-related activities, which implies the consumption of a …
Core–shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine
BM Ladeira, CA Custódio, JF Mano - Biomaterials Science, 2022 - pubs.rsc.org
The fabrication of scaffolds that accurately recreate the architecture of living tissues is a
major challenge in the field of tissue engineering and regenerative medicine. Core–shell …
major challenge in the field of tissue engineering and regenerative medicine. Core–shell …
Cell encapsulation systems toward modular tissue regeneration: from immunoisolation to multifunctional devices
In the primordial cell encapsulation systems, the main goal is to treat endocrine diseases
avoiding the action of the immune system. Although lessons afforded by such systems are of …
avoiding the action of the immune system. Although lessons afforded by such systems are of …
Capacitive interdigitated system of high osteoinductive/conductive performance for personalized acting-sensing implants
BM de Sousa, CR Correia, JAF Ferreira… - NPJ Regenerative …, 2021 - nature.com
Replacement orthopedic surgeries are among the most common surgeries worldwide, but
clinically used passive implants cannot prevent failure rates and inherent revision …
clinically used passive implants cannot prevent failure rates and inherent revision …
Dynamic process enhancement on chitosan/gelatin/nano-hydroxyapatite-bone derived multilayer scaffold for osteochondral tissue repair
Accurate repair of osteochondral defects is a great challenge due to the complex structure of
osteochondral defects. The current study aims to prepare a biomimetic osteochondral …
osteochondral defects. The current study aims to prepare a biomimetic osteochondral …
[HTML][HTML] Platelet lysates-based hydrogels incorporating bioactive mesoporous silica nanoparticles for stem cell osteogenic differentiation
Scaffolds for bone tissue regeneration should provide the right cues for stem cell adhesion
and proliferation, but also lead to their osteogenic differentiation. Hydrogels of modified …
and proliferation, but also lead to their osteogenic differentiation. Hydrogels of modified …
[HTML][HTML] Engineering immunomodulatory hydrogels and cell-laden systems towards bone regeneration
The well-known synergetic interplay between the skeletal and immune systems has
changed the design of advanced bone tissue engineering strategies. The immune system is …
changed the design of advanced bone tissue engineering strategies. The immune system is …