Cell-penetrating peptides derived from animal venoms and toxins

G Rádis-Baptista - Toxins, 2021 - mdpi.com
Cell-penetrating peptides (CPPs) comprise a class of short polypeptides that possess the
ability to selectively interact with the cytoplasmic membrane of certain cell types, translocate …

Hitchhiking with nature: snake venom peptides to fight cancer and superbugs

C Pérez-Peinado, S Defaus, D Andreu - Toxins, 2020 - mdpi.com
For decades, natural products in general and snake venoms (SV) in particular have been a
rich source of bioactive compounds for drug discovery, and they remain a promising …

Antibiofilm Activity on Candida albicans and Mechanism of Action on Biomembrane Models of the Antimicrobial Peptide Ctn[15–34]

FLL Aguiar, NC Santos… - International journal of …, 2020 - mdpi.com
Ctn [15–34], the C-terminal fragment of crotalicidin, an antimicrobial peptide from the South
American rattlesnake Crotalus durissus terrificus venom, displays remarkable anti-infective …

Past, present, and future of naturally occurring antimicrobials related to snake venoms

N Oguiura, L Sanches, PV Duarte, MA Sulca-López… - Animals, 2023 - mdpi.com
Simple Summary A critical global health problem is microbial resistance to antibiotics. In
order to further discuss this issue and search for practical means to overcome such …

The Antimicrobial Activity of Omiganan Alone and In Combination against Candida Isolated from Vulvovaginal Candidiasis and Bloodstream Infections

D Żyrek, A Wajda, P Czechowicz, J Nowicka… - Antibiotics, 2021 - mdpi.com
Fungi from the Candida genus are widespread commensals and, at the same time, are the
leading cause of fungal infections worldwide. For instance, vulvovaginal candidiasis (VVC) …

Antifungal In Vitro Activity of Pilosulin- and Ponericin-Like Peptides from the Giant Ant Dinoponera quadriceps and Synergistic Effects with Antimycotic Drugs

HV Dodou Lima, CS de Paula Cavalcante… - Antibiotics, 2020 - mdpi.com
Venoms from ants comprise a rich source of bioactive peptides, including antimicrobial
peptides. From the proteome and peptidome of the giant ant Dinoponera quadriceps venom …

Antifungal Activity of Linear and Disulfide-Cyclized Ultrashort Cationic Lipopeptides Alone and in Combination with Fluconazole against Vulvovaginal Candida spp.

P Czechowicz, D Neubauer, J Nowicka, W Kamysz… - Pharmaceutics, 2021 - mdpi.com
Vulvovaginal candidiasis (VVC) occurs in over 75% of women at least once during their
lifetime and is an infection that significantly affects their health. Candida strains resistant to …

[HTML][HTML] Antimicrobial peptides and proteins against drug-resistant pathogens

Y Wang, M Song, W Chang - The Cell Surface, 2024 - Elsevier
The rise of drug-resistant pathogens, driven by the misuse and overuse of antibiotics, has
created a formidable challenge for global public health. Antimicrobial peptides and proteins …

The anti-infective crotalicidin peptide analog RhoB-Ctn [1–9] is harmless to bovine oocytes and able to induce parthenogenesis in vitro

AT Dos Santos, S Kumar, JV da Silva Albuquerque… - Toxicon, 2023 - Elsevier
Crotalicidin is a cathelicidin-related anti-infective (antimicrobial) peptide expressed in the
venom glands of the South American rattlesnake Crotalus durissus terrificus. Congener …

Preparation of PLGA Nanoparticles Loaded with the Anti-Infective Ctn [15-34] Peptide for Antifungal Application

AP Santos, RCR Oliveira, BO Louchard… - Brazilian Archives of …, 2023 - SciELO Brasil
This article aims to report the preparation and optimized formulation of Ctn [15-34], a
designed anti-infective peptide, with poly (lactic acid-co-glycolic acid), PLGA, nanoparticles …