The fundamental roles that peptides and proteins play in today's biology makes it almost
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …

The origin of life is a fascinating, unresolved problem whose deciphering would have
important scientific, epistemological and social implications. Over time, philosophers and …

The process by which chemistry can give rise to biology remains one of the biggest
mysteries in contemporary science. The de novo synthesis and origin of life both require the …

Self‐replication is a fundamental concept. The idea of an entity that can repeatedly create
more of itself has captured the imagination of many thinkers from von Neumann to …

Conspectus As the remit of chemistry expands beyond molecules to systems, new synthetic
targets appear on the horizon. Among these, life represents perhaps the ultimate synthetic …

Addressing the emergence of life from a systems biology perspective, this new edition has
undergone extensive revision, reflecting changes in scientific understanding and evolution …

The dissection and subsequent reassembly of a protein from peptidic fragments provides an
avenue for controlling its tertiary structure and hence its function. Here, we describe a …

The two-volume Encyclopedia of Supramolecular Chemistry offers authoritative, centralized
information on a rapidly expanding interdisciplinary field. User-friendly and high-quality …

The emergence of biochemical homochirality was a key step in the origin of life, yet prebiotic
mechanisms for chiral separation are not well constrained. Here we demonstrate a …

Among the key characteristics of living systems are their ability to self‐replicate and the fact
that they exist in an open system away from equilibrium. Herein, we show how the outcome …