Developmental trajectory of cognitive impairment in bipolar disorder: comparison with schizophrenia

E Bora - European Neuropsychopharmacology, 2015 - Elsevier
Both schizophrenia and bipolar disorder (BP) are associated with neurocognitive deficits.
However, it has been suggested that schizophrenia, but not BP, is characterised by …

Neurodevelopmental origins of bipolar disorder: iPSC models

KS O'Shea, MG McInnis - Molecular and Cellular Neuroscience, 2016 - Elsevier
Bipolar disorder (BP) is a chronic neuropsychiatric condition characterized by pathological
fluctuations in mood from mania to depression. Adoption, twin and family studies have …

Clinical and neurocognitive predictors of functional outcome in bipolar euthymic patients: a long-term, follow-up study

CM Bonnín, A Martínez-Arán, C Torrent… - Journal of affective …, 2010 - Elsevier
OBJECTIVE: To identify clinical and neurocognitive predictors of long-term functional
outcome in patients with bipolar disorder METHODS: A total of 32 subjects who met criteria …

Neurocognition in bipolar disorders—a closer look at comorbidities and medications

V Balanzá-Martínez, G Selva, A Martínez-Arán… - European Journal of …, 2010 - Elsevier
The last decade has witnessed a growing interest in the neuropsychological study of bipolar
disorder (BD). This chronic mood disorder is associated with persistent neurocognitive …

Affective versus non-affective first episode psychoses: A longitudinal study

C Torrent, M Reinares, A Martinez-Arán… - Journal of affective …, 2018 - Elsevier
Objective This study aimed to assess (1) whether there were clinical, neuropsychological
and functional differences between and within affective and non-affective psychoses at …

[HTML][HTML] Potentially repurposable drugs for schizophrenia identified from its interactome

KB Karunakaran, S Chaparala, MK Ganapathiraju - Scientific reports, 2019 - nature.com
We previously presented the protein-protein interaction network of schizophrenia associated
genes, and from it, the drug-protein interactome which showed the drugs that target any of …

[HTML][HTML] Calcium-dependent intracellular signal pathways in primary cultured adipocytes and ANK3 gene variation in patients with bipolar disorder and healthy …

A Hayashi, K Le Gal, K Södersten, D Vizlin-Hodzic… - Molecular …, 2015 - nature.com
Bipolar disorder (BD) is a chronic psychiatric disorder of public health importance affecting>
1% of the Swedish population. Despite progress, patients still suffer from chronic mood …

A novel relationship for schizophrenia, bipolar and major depressive disorder Part 3: Evidence from chromosome 3 high density association screen

X Chen, F Long, B Cai, X Chen… - Journal of Comparative …, 2018 - Wiley Online Library
Familial clustering of schizophrenia (SCZ), bipolar disorder (BPD), and major depressive
disorder (MDD) was systematically reported (Aukes et al, Genet Med 2012, 14, 338‐341) …

[HTML][HTML] Double-edged sword of tumour suppressor genes in schizophrenia

C Zhuo, D Wang, C Zhou, C Chen, J Li… - Frontiers in Molecular …, 2019 - frontiersin.org
Schizophrenia (SCZ) is a common psychiatric disorder with polygenetic pathogenesis.
Among the many identified candidate genes and loci, the group of tumour suppressor genes …

[HTML][HTML] Interneuron heterotopia in the Lis1 mutant mouse cortex underlies a structural and functional schizophrenia-like phenotype

R Garcia-Lopez, A Pombero, A Estirado… - Frontiers in Cell and …, 2021 - frontiersin.org
LIS1 is one of the principal genes related to Type I lissencephaly, a severe human brain
malformation characterized by an abnormal neuronal migration in the cortex during …