Anxiety disorders are the most common mental diseases. Anxiety and the associated
physical symptoms may disturb social and occupational life and increase the risk of somatic …

Background Anxiety in relation to surgery is a well‐known problem. Melatonin offers an
atoxic alternative to benzodiazepines in ameliorating this condition in the pre‐and …

We conducted this study to assess long‐term melatonin treatment course, effectiveness and
safety in children with attention‐deficit/hyperactivity disorder (ADHD) and chronic sleep …

Exogenous melatonin is used in a number of situations, first and foremost in the treatment of
sleep disorders and jet leg. However, the hypnotic, antinociceptive, and anticonvulsant …

Melatonin is a remarkable molecule with diverse physiological functions. Some of its effects
are mediated by receptors while other, like cytoprotection, seem to depend on direct and …

Background Anxiety in relation to surgery is a well‐known problem. Melatonin offers an
alternative treatment to benzodiazepines for ameliorating this condition in the preoperative …

This study analyzes the results of clinical trials of treatments with melatonin conducted in
children, mostly focused on sleep disorders of different origin. Melatonin is beneficial not …

Postoperative neurocognitive disorder (PND) increases the length of hospital stay, mortality,
and risk of long-term cognitive impairment. Perioperative sleep disturbance is prevalent and …

Melatonin, an endogenously produced indoleamine, is a highly effective antioxidant, free
radical scavenger, and a primary circadian regulator. Melatonin has important antioxidant …

What is known and Objective It is estimated that 60% of children undergoing anaesthesia
develop severe preoperative anxiety. The anxiety is associated with adverse reactions …