Background Cancer is the most prevalent cause of death globally, and radiotherapy is
considered the standard of care for most solid tumors, including lung, breast, esophageal …

Colon cancer affects both men and women and is the world's second most significant cause
of cancer-related mortality. Colon cancer death rates have risen worldwide due to the …

Many cellular processes in cancer are attributed to kinase signaling networks. V-akt murine
thymoma viral oncogene homolog (AKT) plays a major role in the PI3K/AKT signaling …

Circular RNAs (circRNAs), covalently closed noncoding RNAs, are widely expressed in
eukaryotes and viruses. They can function by regulating target gene expression, linear RNA …

The bone microenvironment is an ideal fertile soil for both primary and secondary tumors to
seed. The occurrence and development of osteosarcoma, as a primary bone tumor, is …

Apigenin is a common dietary flavonoid that is abundantly present in many fruits, vegetables
and Chinese medicinal herbs and serves multiple physiological functions, such as strong …

Cancer is one of the leading causes of death across the world. Different environmental and
anthropogenic factors initiate mutations in different functional genes of growth factors and …

Signal transducer and activator of transcription 3 (STAT3) is one of seven STAT family
members involved with the regulation of cellular growth, differentiation and survival. STAT …

Colorectal cancer (CRC) affects 1 in 23 males and 1 in 25 females, making it the third most
common cancer. With roughly 608000 deaths worldwide, CRC accounts for 8% of all cancer …

Abstract Background Circular RNAs (circRNAs), a class of noncoding RNAs (ncRNAs), may
modulate gene expression by binding to miRNAs. Additionally, recent studies show that …