Microengineered platforms for cell mechanobiology

DH Kim, PK Wong, J Park… - Annual review of …, 2009 - annualreviews.org
Mechanical forces play important roles in the regulation of various biological processes at
the molecular and cellular level, such as gene expression, adhesion, migration, and cell …

Cell stretching devices as research tools: engineering and biological considerations

H Kamble, MJ Barton, M Jun, S Park, NT Nguyen - Lab on a Chip, 2016 - pubs.rsc.org
Cells within the human body are subjected to continuous, cyclic mechanical strain caused
by various organ functions, movement, and growth. Cells are well known to have the ability …

Biomechanical characterization at the cell scale: present and prospects

F Basoli, SM Giannitelli, M Gori, P Mozetic… - Frontiers in …, 2018 - frontiersin.org
The rapidly growing field of mechanobiology demands for robust and reproducible
characterization of cell mechanical properties. Recent achievements in understanding the …

Cell culture on MEMS platforms: a review

M Ni, WH Tong, D Choudhury, NAA Rahim… - International journal of …, 2009 - mdpi.com
Microfabricated systems provide an excellent platform for the culture of cells, and are an
extremely useful tool for the investigation of cellular responses to various stimuli …

[HTML][HTML] Mechanobiology in lung epithelial cells: measurements, perturbations, and responses

CM Waters, E Roan, D Navajas - Comprehensive Physiology, 2012 - ncbi.nlm.nih.gov
Epithelial cells of the lung are located at the interface between the environment and the
organism and serve many important functions including barrier protection, fluid balance …

Scaffolds for bone tissue engineering: role of surface patterning on osteoblast response

J Mitra, G Tripathi, A Sharma, B Basu - Rsc Advances, 2013 - pubs.rsc.org
The fabrication of tissue engineering scaffolds necessitates amalgamation of a multitude of
attributes including a desirable porosity to encourage vascular invasion, desired surface …

Affinity chromatography approaches to overcome the challenges of purifying plasmid DNA

F Sousa, DMF Prazeres, JA Queiroz - Trends in biotechnology, 2008 - cell.com
The diversity of biomolecules present in plasmid DNA (pDNA)-containing extracts and the
structural and chemical similarities between pDNA and impurities are some of the main …

An array of 100 μm× 100 μm dielectric elastomer actuators with 80% strain for tissue engineering applications

S Akbari, HR Shea - Sensors and Actuators A: Physical, 2012 - Elsevier
Biological cells modulate their behavior, express genes, proliferate or differentiate in
response to mechanical strains ranging from 1% to 20%. There currently exists no technique …

Microfabrication and characterization of an array of dielectric elastomer actuators generating uniaxial strain to stretch individual cells

S Akbari, HR Shea - Journal of Micromechanics and …, 2012 - iopscience.iop.org
Cells regulate their behavior in response to mechanical strains. Cell cultures to study
mechanotransuction are typically cm 2 in area, far too large to monitor single cell response …

The potential of MEMS for advancing experiments and modeling in cell mechanics

O Loh, A Vaziri, HD Espinosa - Experimental Mechanics, 2009 - Springer
Response to mechanical stimuli largely dictates cellular form and function. A host of
extraordinary yet unexplained responses have been identified within the hierarchical cell …