Imaging and biophysical modelling of thrombogenic mechanisms in atrial fibrillation and stroke
A Qureshi, GYH Lip, DA Nordsletten… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) underlies almost one third of all ischaemic strokes, with the left atrial
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …
A comprehensive stroke risk assessment by combining atrial computational fluid dynamics simulations and functional patient data
Stroke, a major global health concern often rooted in cardiac dynamics, demands precise
risk evaluation for targeted intervention. Current risk models, like the CHA 2 DS 2-VASc …
risk evaluation for targeted intervention. Current risk models, like the CHA 2 DS 2-VASc …
[HTML][HTML] A novel mono-physics particle-based approach for the simulation of cardiovascular fluid-structure interaction problems
Background and objective Fluid-structure interaction (FSI) is required in the study of several
cardiovascular engineering problems were the mutual interaction between the pulsatile …
cardiovascular engineering problems were the mutual interaction between the pulsatile …
Elevated atrial blood stasis in paroxysmal atrial fibrillation during sinus rhythm: a patient-specific computational fluid dynamics study
Introduction Atrial fibrillation (AF) is associated with an increased risk of stroke, often caused
by thrombi that form in the left atrium (LA), and especially in the left atrial appendage (LAA) …
by thrombi that form in the left atrium (LA), and especially in the left atrial appendage (LAA) …
Slow blood-flow in the left atrial appendage is associated with stroke in atrial fibrillation patients
Background Atrial fibrillation (AF) patients are at high risk of stroke with∼ 90% clots
originating from the left atrial appendage (LAA). Clinical understanding of blood-flow based …
originating from the left atrial appendage (LAA). Clinical understanding of blood-flow based …
Modelling of thrombus formation using smoothed particle hydrodynamics method
In this paper a novel model, based on the smoothed particle hydrodynamics (SPH) method,
is proposed to simulate thrombus formation. This describes the main phases of the …
is proposed to simulate thrombus formation. This describes the main phases of the …
A reduced order model formulation for left atrium flow: an atrial fibrillation case
A data-driven reduced order model (ROM) based on a proper orthogonal decomposition-
radial basis function (POD-RBF) approach is adopted in this paper for the analysis of blood …
radial basis function (POD-RBF) approach is adopted in this paper for the analysis of blood …
[HTML][HTML] Effect of the apron in the mechanical characterisation of hyperelastic materials by means of biaxial testing: A new method to improve accuracy
S Di Leonardo, A Monteleone, P Caruso… - Journal of the …, 2024 - Elsevier
Biological soft tissues and polymers used in biomedical applications (eg in the
cardiovascular area) are hyperelastic incompressible materials that commonly operate …
cardiovascular area) are hyperelastic incompressible materials that commonly operate …
[HTML][HTML] Fluid-structure interaction analysis of the thromboembolic risk in the left atrial appendage under atrial fibrillation: Effect of hemodynamics and morphological …
Background Complications of atrial fibrillation (AF) include ischemic events originating
within the left atrial appendage (LAA), a protrusion of the left atrium with variable …
within the left atrial appendage (LAA), a protrusion of the left atrium with variable …
Impact of left atrial wall motion assumptions in fluid simulations on proposed predictors of thrombus formation
HA Kjeldsberg, C Albors, J Mill… - International Journal …, 2024 - Wiley Online Library
Atrial fibrillation (AF) poses a significant risk of stroke due to thrombus formation, which
primarily occurs in the left atrial appendage (LAA). Medical image‐based computational fluid …
primarily occurs in the left atrial appendage (LAA). Medical image‐based computational fluid …