Cardiovascular disease is the leading contributor to years lost due to disability or premature
death among adults. Current efforts focus on risk prediction and risk factor mitigation ‚which …

Purpose Genetic testing has advanced significantly since the publication of the 2011
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …

Background: Each of the cardiomyopathies, classically categorized as hypertrophic
cardiomyopathy, dilated cardiomyopathy (DCM), and arrhythmogenic right ventricular …

Epilepsy, defined by the occurrence of two or more unprovoked seizures or one unprovoked
seizure with a propensity for others, affects 0.64% of the population and can lead to …

There is increasing evidence regarding the prevalence of genetic cardiomyopathies, for
which arrhythmias may be the first presentation. Ventricular and atrial arrhythmias …

Importance Idiopathic dilated cardiomyopathy (DCM) aggregates in families, and early
detection in at-risk family members can provide opportunity to initiate treatment prior to late …

Genetic diseases that affect the cardiovascular system are relatively common and include
cardiac channelopathies, cardiomyopathies, aortopathies, hypercholesterolemias, and …

Successful proband‐mediated family communication and subsequent cascade genetic
testing uptake requires interventions that present information clearly, in sufficient detail, and …

Noncompaction cardiomyopathy (NCCM) has gained increasing attention over the past
twenty years, but in daily clinical practice NCCM is still rarely considered. So far, there are …

Polygenic diseases, which are genetic disorders caused by the combined action of multiple
genes, pose unique and significant challenges for the diagnosis and management of …