Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments

PH Lysaker, ML Pattison, BL Leonhardt… - World …, 2018 - Wiley Online Library
Poor insight in schizophrenia is prevalent across cultures and phases of illness. In this
review, we examine the recent research on the relationship of insight with behavior, mood …

Comorbid major depressive disorder in schizophrenia: a systematic review and meta-analysis

D Etchecopar-Etchart, T Korchia… - Schizophrenia …, 2021 - academic.oup.com
Comorbid major depressive disorder (MDD) in schizophrenia (SZ; SZ-MDD) has been
identified as a major prognostic factor. However, the prevalence and associated factors of …

Insight and medication adherence in schizophrenia: an analysis of the CATIE trial

J Kim, M Ozzoude, S Nakajima, P Shah… - …, 2020 - Elsevier
Adherence to antipsychotic medication is critical for the treatment of patients with
schizophrenia. Impaired insight into illness is one of the principal drivers of medication …

Medication adherence in schizophrenia: The role of insight, therapeutic alliance and perceived trauma associated with psychiatric care

A Tessier, L Boyer, M Husky, F Baylé, PM Llorca… - Psychiatry …, 2017 - Elsevier
Medication non adherence in schizophrenia is a major cause of relapse and hospitalization
and remains for clinicians an important challenge. This study investigates the associations …

Family psychoeducation to improve outcome in caregivers and patients with schizophrenia: a randomized clinical trial

A Tessier, K Roger, A Gregoire, P Desnavailles… - Frontiers in …, 2023 - frontiersin.org
Introduction Schizophrenia is recognized for its severe impact on both patients and
caregivers. In a 12-month follow-up randomized clinical trial, we aimed to measure the …

Metacognitive deficits predict impaired insight in schizophrenia across symptom profiles: a latent class analysis

PH Lysaker, E Gagen, A Wright, JL Vohs… - Schizophrenia …, 2019 - academic.oup.com
The integrated model of insight in schizophrenia suggests that poor insight is the result of
multiple factors which compromise persons' abilities to integrate streams of information into …

Decriminalizing mental illness: specialized policing responses

C Dempsey, C Quanbeck, C Bush, K Kruger - CNS spectrums, 2020 - cambridge.org
De-institutionalization of mental health patients has evolved, over nearly 3 generations now,
to a status quo of mental health patients experiencing myriad contacts with first-responders …

Schizophrenia: Antipsychotics and drug development

G Remington, MK Hahn, SM Agarwal, A Chintoh… - Behavioural Brain …, 2021 - Elsevier
The introduction of chlorpromazine and the work that ensued provided the foundation to
reposition schizophrenia as a biological illness. The present paper follows the evolution of …

Daily functioning and symptom factors contributing to attitudes toward antipsychotic treatment and treatment adherence in outpatients with schizophrenia spectrum …

J Leijala, O Kampman, J Suvisaari, S Eskelinen - BMC psychiatry, 2021 - Springer
Background Poor adherence and negative attitudes to treatment are common clinical
problems when treating psychotic disorders. This study investigated how schizophrenia core …

Characteristics associated with self-reported medication adherence in persons with psychosis referred to psychosocial rehabilitation centers

H Verdoux, C Quiles, L Bon, I Chéreau-Boudet… - European Archives of …, 2021 - Springer
The aim of the present study was to explore the characteristics of psychotropic treatment and
of psychosocial functioning associated with self-reported medication adherence in persons …