Molecular mechanisms of antiviral agents against dengue virus

MF Lee, YS Wu, CL Poh - Viruses, 2023 - mdpi.com
Dengue is a major global health threat causing 390 million dengue infections and 25,000
deaths annually. The lack of efficacy of the licensed Dengvaxia vaccine and the absence of …

The multiples fates of the flavivirus RNA genome during pathogenesis

C Mazeaud, W Freppel, L Chatel-Chaix - Frontiers in genetics, 2018 - frontiersin.org
The Flavivirus genus comprises many viruses (including dengue, Zika, West Nile and yellow
fever viruses) which constitute important public health concerns worldwide. For several of …

Molecular insights into the flavivirus replication complex

K Van den Elsen, JP Quek, D Luo - Viruses, 2021 - mdpi.com
Flaviviruses are vector-borne RNA viruses, many of which are clinically relevant human viral
pathogens, such as dengue, Zika, Japanese encephalitis, West Nile and yellow fever …

Tick-borne flaviviruses, with a focus on Powassan virus

G Kemenesi, K Bányai - Clinical microbiology reviews, 2018 - Am Soc Microbiol
The tick-borne pathogen Powassan virus is a rare cause of encephalitis in North America
and the Russian Far East. The number of documented cases described since the discovery …

Dengue and Zika viruses: Epidemiological history, potential therapies, and promising vaccines

NM Silva, NC Santos, IC Martins - Tropical medicine and infectious …, 2020 - mdpi.com
Dengue virus (DENV), which can lead to fatal hemorrhagic fever, affects 390 million people
worldwide. The closely related Zika virus (ZIKV) causes microcephaly in newborns and …

Subgenomic flaviviral RNAs: What do we know after the first decade of research

A Slonchak, AA Khromykh - Antiviral research, 2018 - Elsevier
The common feature of flaviviral infection is the accumulation of abundant virus-derived
noncoding RNA, named flaviviral subgenomic RNA (sfRNA) in infected cells. This RNA …

Integrative analysis of Zika virus genome RNA structure reveals critical determinants of viral infectivity

P Li, Y Wei, M Mei, L Tang, L Sun, W Huang, J Zhou… - Cell host & …, 2018 - cell.com
Zika virus (ZIKV) strains can be classified into the ancestral African and contemporary Asian
lineages, with the latter responsible for recent epidemics associated with neurological …

Innate and adaptive immune evasion by dengue virus

MF Lee, GZ Voon, HX Lim, ML Chua… - Frontiers in Cellular and …, 2022 - frontiersin.org
Dengue is a mosquito-borne disease which causes significant public health concerns in
tropical and subtropical countries. Dengue virus (DENV) has evolved various strategies to …

Human Usutu virus infections in Europe: a new risk on horizon?

D Cadar, Y Simonin - Viruses, 2022 - mdpi.com
The Usutu virus (USUV), a neurotropic mosquito-borne flavivirus discovered in 1959 in
South Africa, has spread over the last twenty years across the European continent. This virus …

An updated analysis of variations in SARS-CoV-2 genome

OM Uğurel, O Ata, D BALIK - Turkish Journal of Biology, 2020 - journals.tubitak.gov.tr
A novel pathogen, named SARS-CoV-2, has caused an unprecedented worldwide
pandemic in the first half of 2020. As the SARS-CoV-2 genome sequences have become …