Neurodegeneration is a phenomenon that occurs in the central nervous system through the
hallmarks associating the loss of neuronal structure and function. Neurodegeneration is …

Background Animal studies show that peripheral inflammatory stimuli may activate
microglial cells in the brain implicating an important role for microglia in sepsis-associated …

Neuroinflammatory response is primarily a protective mechanism in the brain. However,
excessive and chronic inflammatory responses can lead to deleterious effects involving …

Background Long-term exposure to fine particles (particulate matter≤ 2.5 μm; PM2. 5) has
been consistently linked to heart and lung disease. Recently, there has been increased …

The central nervous system is emerging as an important target for adverse health effects of
air pollution, where it may contribute to neurodevelopmental and neurodegenerative …

Sialic acids are a diverse family of monosaccharides widely expressed on all cell surfaces of
vertebrates and so‐called “higher” invertebrates, and on certain bacteria that interact with …

Exposure to ambient air pollution is a serious and common public health concern associated
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …

Systemic infection and drugs with anticholinergic effects are well-recognised and prevalent
risk factors for delirium in elderly people. Experimental findings and neuropathological …

Periodontitis is an oral chronic infection/inflammatory condition, identified as a source of
mediators of inflammation into the blood circulation, which may contribute to exacerbate …

Recently, the inflammatory and neurodegenerative (I&ND) hypothesis of depression was
formulated (Maes et al., 2009), ie the neurodegeneration and reduced neurogenesis that …