Alzheimer's disease (AD) is the most common cause of neurodegenerative dementia, whilst
Parkinson's disease (PD) is a neurodegenerative movement disorder. These two …

In the aging process and central nervous system (CNS) diseases, the functions of the
meningeal lymphatic vessels (MLVs) are impaired. Alterations in MLVs have been observed …

Age-related cognitive decline is associated with dysfunctional lymphatic drainage of
cerebrospinal fluid (CSF) through meningeal lymphatic vessels. In this study, intrathecal …

Brain vascular health appears to be critical for preventing the development of amyotrophic
lateral sclerosis (ALS) and slowing its progression. ALS patients often demonstrate …

The aging of the global population poses significant scientific challenges. Moreover, the
biological process of aging is the most significant risk factor for most chronic illnesses; …

Traumatic brain injury (TBI) and stroke pose major health challenges, impacting millions of
individuals globally. Once considered solely acute events, these neurological conditions are …

The glymphatic system and the meningeal lymphatic vessels provide a pathway for transport
of solutes and clearance of toxic material from the brain. Of specific relevance to ALS, this is …

The mammalian nervous system is impacted by aging. Aging alters brain architecture, is
associated with molecular damage, and can manifest with cognitive and motor deficits that …

The central nervous system (CNS) has been viewed as an immunologically privileged site,
but emerging works are uncovering a large array of neuroimmune interactions primarily …

Rationale: Hydrocephalus is a substantial complication after intracerebral hemorrhage (ICH)
or intraventricular hemorrhage (IVH) that leads to impaired cerebrospinal fluid (CSF) …