Cyclodextrin-based ocular drug delivery systems: A comprehensive review

Q Wang, A Zhang, L Zhu, X Yang, G Fang… - Coordination Chemistry …, 2023 - Elsevier
Cyclodextrin (CD), a class of cyclic oligosaccharides with an external hydrophilic surface
and a central hydrophobic cavity is recognized as a promising pharmaceutical excipient due …

Cyclodextrins

SV Kurkov, T Loftsson - International journal of pharmaceutics, 2013 - Elsevier
Although cyclodextrins (CDs) have been studied for over 100 years and can be found in at
least 35 pharmaceutical products, they are still regarded as novel pharmaceutical …

[HTML][HTML] Polysaccharides in ocular drug delivery

N Dubashynskaya, D Poshina, S Raik, A Urtti… - Pharmaceutics, 2019 - mdpi.com
Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as
polysaccharide derivatives, have been successfully used to augment drug delivery in the …

[HTML][HTML] Cyclodextrin multicomponent complexes: Pharmaceutical applications

V Aiassa, C Garnero, MR Longhi, A Zoppi - Pharmaceutics, 2021 - mdpi.com
Cyclodextrins (CDs) are naturally available water-soluble cyclic oligosaccharides widely
used as carriers in the pharmaceutical industry for their ability to modulate several properties …

Cyclodextrins for drug delivery

AL Laza-Knoerr, R Gref, P Couvreur - Journal of drug targeting, 2010 - Taylor & Francis
Cyclodextrins (CDs) are macrocyclic oligosaccharides composed of α (1, 4)-linked
glucopyranose subunits. These molecules possess a cage-like supramolecular structure …

Cyclodextrins and topical drug delivery to the anterior and posterior segments of the eye

T Loftsson, E Stefánsson - International journal of pharmaceutics, 2017 - Elsevier
It is generally believed that it is virtually impossible to obtain therapeutic drug concentrations
in the posterior segment of the eye after topical application of aqueous, low viscosity eye …

Bioadhesive and biocompatible films as wound dressing materials based on a novel dendronized chitosan loaded with ciprofloxacin

MC García, AA Aldana, LI Tártara, F Alovero… - Carbohydrate …, 2017 - Elsevier
The bioadhesive polymeric films as topical drug delivery systems are interesting alternatives
to improve the pharmacotherapy and patient compliances. New derivate biomaterials based …

Corneal permeation properties of a charged lipid nanoparticle carrier containing dexamethasone

J Ban, Y Zhang, X Huang, G Deng, D Hou… - International journal …, 2017 - Taylor & Francis
Drug delivery carriers can maintain effective therapeutic concentrations in the eye. To this
end, we developed lipid nanoparticles (L/NPs) in which the surface was modified with …

Novel water-soluble mucoadhesive carbosilane dendrimers for ocular administration

I Bravo-Osuna, M Vicario-de-la-Torre… - Molecular …, 2016 - ACS Publications
The purpose of this research was to determine the potential use of water-soluble anionic
and cationic carbosilane dendrimers (generations 1–3) as mucoadhesive polymers in …

Cyclodextrin-based formulation of carbonic anhydrase inhibitors for ocular delivery–a review

P Jansook, HM Hnin, T Loftsson… - International Journal of …, 2021 - Elsevier
Carbonic anhydrase inhibitors (CAIs) are used as systemic and topical agents for lowering
intraocular pressure (IOP) in patients with glaucoma. Owing to the wide distribution of CAs …