Antioxidant effects and mechanisms of medicinal plants and their bioactive compounds for the prevention and treatment of type 2 diabetes: an updated review

JO Unuofin, SL Lebelo - Oxidative medicine and cellular …, 2020 - Wiley Online Library
Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …

Diabetic cardiomyopathy: molecular mechanisms, detrimental effects of conventional treatment, and beneficial effects of natural therapy

B Parim, VV Sathibabu Uddandrao, G Saravanan - Heart Failure Reviews, 2019 - Springer
Diabetic complications are among the largely exigent health problems currently.
Cardiovascular complications, including diabetic cardiomyopathy (DCM), account for more …

[HTML][HTML] Involvement of growth factors in diabetes mellitus and its complications: A general review

GJ Shi, GR Shi, J Zhou, W Zhang, C Gao… - Biomedicine & …, 2018 - Elsevier
Diabetes mellitus (DM) is a major endocrine metabolic disease and is marked by a lack of
insulin. The complication of DM is one of the most difficult problems in medicine. The initial …

Pathophysiology of diabetes mellitus complications: Metabolic events and control

FO Ohiagu, PC Chikezie… - … Research and Therapy, 2021 - bmrat.biomedpress.org
Background: Diabetes mellitus (DM) is a metabolic disorder that is characterized by
hyperglycemia and glucose intolerance, which is associated with impaired insulin secretion …

[HTML][HTML] S-Allyl-L-Cysteine—A garlic bioactive: Physicochemical nature, mechanism, pharmacokinetics, and health promoting activities

N Rais, A Ved, R Ahmad, M Kumar, MD Barbhai… - Journal of Functional …, 2023 - Elsevier
Abstract S-allyl-L-cysteine (SAC) is a sulfur-containing substance found in aged garlic
extract (AGE), which has been observed to have numerous biological activities, including …

Restorative potentiality of S-allylcysteine against diabetic nephropathy through attenuation of oxidative stress and inflammation in streptozotocin–nicotinamide …

VV Sathibabu Uddandrao, P Brahmanaidu… - European journal of …, 2019 - Springer
Aim In the present study, we evaluated the therapeutic potentiality of S-allylcysteine (SAC) in
streptozotocin (STZ)–nicotinamide (NAD)-induced diabetic nephropathy (DN) in …

Polyherbal formulation ameliorates diabetic cardiomyopathy through attenuation of cardiac inflammation and oxidative stress via NF-κB/Nrf-2/HO-1 pathway in …

VVS Uddandrao, B Parim, S Singaravel… - Journal of …, 2022 - journals.lww.com
The present study was intended to evaluate the effect of polyherbal formulation (PHF) made
with 3 nutraceuticals, such as Piper nigrum, Terminalia paniculata, and Bauhinia purpurea …

Reversal of endothelial dysfunction in aorta of streptozotocin-nicotinamide-induced type-2 diabetic rats by S-Allylcysteine

P Brahmanaidu, VVS Uddandrao, V Sasikumar… - Molecular and cellular …, 2017 - Springer
Dietary measures and plant–based therapies as prescribed by native systems of medicine
have gained attraction among diabetics with claims of efficacy. The present study …

Phenolic compounds: the inhibition effect on polyol pathway enzymes

HE Aslan, Ş Beydemir - Chemico-biological interactions, 2017 - Elsevier
The polyol pathway called as sorbitol way is a small part of glycose metabolism. The
pathway is regarded as an important element in the pathogenesis of various diabetic …

Obesity-alleviating potential of asiatic acid and its effects on ACC1, UCP2, and CPT1 mRNA expression in high fat diet-induced obese Sprague–Dawley rats

P Rameshreddy, VVS Uddandrao… - Molecular and cellular …, 2018 - Springer
The present study evaluated the effects of asiatic acid (AA), a pentacyclic triterpenoid from
Centella asiatica on lipid metabolism parameters in a rat model of obesity induced using a …