Heterochromatin is most often associated with eukaryotic organisms. Yet, bacteria also
contain areas with densely protein-occupied chromatin that appear to silence gene …

Messenger RNAs (mRNAs) convey genetic information from the DNA genome to proteins
and thus lie at the heart of gene expression and regulation of all cellular activities. Live cell …

Super-resolution light microscopy (SRM) offers a unique opportunity for diffraction-unlimited
imaging of biomolecular activities in living cells. To realize such potential, genetically …

Biomolecular condensates play a key role in organizing RNAs and proteins into
membraneless organelles. Bacterial RNP-bodies (BR-bodies) are a biomolecular …

The ability to locate and identify molecular interactions in cells has significant importance for
understanding protein function and molecular biology. Functionalized metallic nanoparticles …

Single-molecule imaging techniques and single-particle tracking (SPT) of molecules inside
living cells investigate biomolecular dynamics at nanometer spatial resolution and …

High-resolution imaging of biomolecular condensates in living cells is essential for
correlating their properties to those observed through in vitro assays. However, such …

Single-molecule localization microscopy (SMLM) is a powerful super-resolution technique
for elucidating structure and dynamics in the life-and material sciences. Simultaneously …

Bacterial DNA methyltransferases (MTases) function in restriction modification systems, cell
cycle control, and the regulation of gene expression. DnmA is a recently described DNA …

Photothermal heating of nanoparticles has applications in nanomedicine, photocatalysis,
photoelectrochemistry, and data storage, but accurate measurements of temperature at the …