Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
[HTML][HTML] Blood-based biomarkers of inflammation in mild traumatic brain injury: A systematic review
K Visser, M Koggel, J Blaauw, HJ van der Horn… - Neuroscience & …, 2022 - Elsevier
Abstract VISSER, K., M. Koggel, J. Blaauw, HJvd Horn, B. Jacobs, and Jvd Naalt. Blood
based biomarkers of inflammation in mild traumatic brain injury: A systematic review …
based biomarkers of inflammation in mild traumatic brain injury: A systematic review …
Neurofilament light as a biomarker in traumatic brain injury
P Shahim, A Politis, A Van Der Merwe, B Moore… - Neurology, 2020 - AAN Enterprises
Objective To determine whether serum neurofilament light (NfL) correlates with CSF NfL,
traumatic brain injury (TBI) diagnosis, injury severity, brain volume, and diffusion tensor …
traumatic brain injury (TBI) diagnosis, injury severity, brain volume, and diffusion tensor …
S100B, GFAP, UCH-L1 and NSE as predictors of abnormalities on CT imaging following mild traumatic brain injury: a systematic review and meta-analysis of …
Biomarkers such as calcium channel binding protein S100 subunit beta (S100B), glial
fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase L1 (UCH-L1) and neuron …
fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase L1 (UCH-L1) and neuron …
[HTML][HTML] GFAP and S100B: what you always wanted to know and never dared to ask
Traumatic brain injury (TBI) is a major global health issue, with outcomes spanning from
intracranial bleeding, debilitating sequelae, and invalidity with consequences for individuals …
intracranial bleeding, debilitating sequelae, and invalidity with consequences for individuals …
What room for two-dimensional gel-based proteomics in a shotgun proteomics world?
K Marcus, C Lelong, T Rabilloud - Proteomes, 2020 - mdpi.com
Two-dimensional gel electrophoresis was instrumental in the birth of proteomics in the late
1980s. However, it is now often considered as an outdated technique for proteomics—a …
1980s. However, it is now often considered as an outdated technique for proteomics—a …
DAMPs and RAGE pathophysiology at the acute phase of brain injury: an overview
B Balança, L Desmurs, J Grelier… - International Journal of …, 2021 - mdpi.com
Early or primary injury due to brain aggression, such as mechanical trauma, hemorrhage or
is-chemia, triggers the release of damage-associated molecular patterns (DAMPs) in the …
is-chemia, triggers the release of damage-associated molecular patterns (DAMPs) in the …
Heart-type fatty acid-binding protein: an overlooked cardiac biomarker
H Goel, J Melot, MD Krinock, A Kumar… - Annals of …, 2020 - Taylor & Francis
Cardiac troponins (cTn) are currently the standard of care for the diagnosis of acute coronary
syndromes (ACS) in patients presenting to the emergency department (ED) with chest pain …
syndromes (ACS) in patients presenting to the emergency department (ED) with chest pain …
Circulating GFAP and Iba-1 levels are associated with pathophysiological sequelae in the thalamus in a pig model of mild TBI
Serum biomarkers are promising tools for evaluating patients following traumatic brain injury
(TBI). However, their relationship with diffuse histopathology remains unclear. Additionally …
(TBI). However, their relationship with diffuse histopathology remains unclear. Additionally …
[HTML][HTML] Examining four blood biomarkers for the detection of acute intracranial abnormalities following mild traumatic brain injury in older adults
Blood-based biomarkers have been increasingly studied for diagnostic and prognostic
purposes in patients with mild traumatic brain injury (MTBI). Biomarker levels in blood have …
purposes in patients with mild traumatic brain injury (MTBI). Biomarker levels in blood have …