Synthesis, anticancer activity and mechanism of action of new thiazole derivatives
TI de Santana, M de Oliveira Barbosa… - European journal of …, 2018 - Elsevier
Thiazole derivatives are recognized to possess various biological activities as antiparasitic,
antifungal, antimicrobial and antiproliferative. The present work reports the synthesis of 22 …
antifungal, antimicrobial and antiproliferative. The present work reports the synthesis of 22 …
[HTML][HTML] Larvicidal and adulticidal effects of some Egyptian oils against Culex pipiens
Mosquitoes and mosquito-borne diseases represent an increasing global challenge. Plant
extract and/or oils could serve as alternatives to synthetic insecticides. The larvicidal effects …
extract and/or oils could serve as alternatives to synthetic insecticides. The larvicidal effects …
[HTML][HTML] Targeting Aedes aegypti Metabolism with Next-Generation Insecticides
Aedes aegypti is the primary vector of dengue virus (DENV), zika virus (ZIKV), and other
emerging infectious diseases of concern. A key disease mitigation strategy is vector control …
emerging infectious diseases of concern. A key disease mitigation strategy is vector control …
Privileged structures in the design of potential drug candidates for neglected diseases
ACL Leite, JWP Espíndola… - Current Medicinal …, 2019 - ingentaconnect.com
Background: Privileged motifs are recurring in a wide range of biologically active
compounds that reach different pharmaceutical targets and pathways and could represent a …
compounds that reach different pharmaceutical targets and pathways and could represent a …
Synthesis and characterization of nitrile functionalized silver (I)-N-heterocyclic carbene complexes: DNA binding, cleavage studies, antibacterial properties and …
A series of four benzimidazolium based nitrile–functionalized mononuclear–Ag (I)–N-
heterocyclic carbene and binuclear–Ag (I)–N-heterocyclic carbene (Ag (I)–NHC) …
heterocyclic carbene and binuclear–Ag (I)–N-heterocyclic carbene (Ag (I)–NHC) …
Larvicidal activity and in silico studies of cinnamic acid derivatives against Aedes aegypti (Diptera: Culicidae)
SB França, LCB de Lima, CR da Silva Cunha… - Bioorganic & Medicinal …, 2021 - Elsevier
Cinnamic acid derivatives (CAD's) represent a great alternative in the search for insecticides
against Aedes aegypti mosquitoes since they have antimicrobial and insecticide properties …
against Aedes aegypti mosquitoes since they have antimicrobial and insecticide properties …
[HTML][HTML] Anti-liver cancer activity in vitro and in vivo induced by 2-pyridyl 2, 3-thiazole derivatives
TD dos Santos Silva, LM Bomfim… - Toxicology and applied …, 2017 - Elsevier
A total of 24 hybrid compounds containing pyridyl and 1, 3-thiazole moieties were screened
against HL-60 (leukemia), MCF-7 (breast adenocarcinoma), HepG2 (hepatocellular …
against HL-60 (leukemia), MCF-7 (breast adenocarcinoma), HepG2 (hepatocellular …
Halogenated aromatic thiosemicarbazones as potent inhibitors of tyrosinase and melanogenesis
K Hałdys, W Goldeman, M Jewgiński, E Wolińska… - Bioorganic …, 2020 - Elsevier
A set of 21 halogenated thiosemicarbazones (TSCs) have been synthesized and its
inhibitory properties toward activity diphenolase of mushroom tyrosinase and their ability to …
inhibitory properties toward activity diphenolase of mushroom tyrosinase and their ability to …
Cladophialophora bantiana metabolites are efficient in the larvicidal and ovicidal control of Aedes aegypti, and Culex quinquefasciatus and have low toxicity in …
Mosquitoes' current insecticide resistance status in available public health insecticides is a
serious threat to mosquito control initiatives. Microbe-based control agents provide an …
serious threat to mosquito control initiatives. Microbe-based control agents provide an …
Synthesis and evaluation of novel 1, 3, 4-thiadiazole--fluoroquinolone hybrids as antibacterial, antituberculosis, and anticancer agents
A Demirci, KG KARAYEL, E Tatar… - Turkish Journal of …, 2018 - journals.tubitak.gov.tr
Abstract A series of 5-substituted-1, 3, 4-thiadiazole-based fluoroquinolone derivatives were
designed as potential antibacterial and anticancer agents using a molecular hybridization …
designed as potential antibacterial and anticancer agents using a molecular hybridization …