Synthesis, anticancer activity and mechanism of action of new thiazole derivatives

TI de Santana, M de Oliveira Barbosa… - European journal of …, 2018 - Elsevier
Thiazole derivatives are recognized to possess various biological activities as antiparasitic,
antifungal, antimicrobial and antiproliferative. The present work reports the synthesis of 22 …

[HTML][HTML] Larvicidal and adulticidal effects of some Egyptian oils against Culex pipiens

MM Baz, A Selim, IT Radwan, AM Alkhaibari… - Scientific Reports, 2022 - nature.com
Mosquitoes and mosquito-borne diseases represent an increasing global challenge. Plant
extract and/or oils could serve as alternatives to synthetic insecticides. The larvicidal effects …

[HTML][HTML] Targeting Aedes aegypti Metabolism with Next-Generation Insecticides

MJ Conway, DP Haslitt, BM Swarts - Viruses, 2023 - mdpi.com
Aedes aegypti is the primary vector of dengue virus (DENV), zika virus (ZIKV), and other
emerging infectious diseases of concern. A key disease mitigation strategy is vector control …

Privileged structures in the design of potential drug candidates for neglected diseases

ACL Leite, JWP Espíndola… - Current Medicinal …, 2019 - ingentaconnect.com
Background: Privileged motifs are recurring in a wide range of biologically active
compounds that reach different pharmaceutical targets and pathways and could represent a …

Synthesis and characterization of nitrile functionalized silver (I)-N-heterocyclic carbene complexes: DNA binding, cleavage studies, antibacterial properties and …

PO Asekunowo, RA Haque, MR Razali… - European Journal of …, 2018 - Elsevier
A series of four benzimidazolium based nitrile–functionalized mononuclear–Ag (I)–N-
heterocyclic carbene and binuclear–Ag (I)–N-heterocyclic carbene (Ag (I)–NHC) …

Larvicidal activity and in silico studies of cinnamic acid derivatives against Aedes aegypti (Diptera: Culicidae)

SB França, LCB de Lima, CR da Silva Cunha… - Bioorganic & Medicinal …, 2021 - Elsevier
Cinnamic acid derivatives (CAD's) represent a great alternative in the search for insecticides
against Aedes aegypti mosquitoes since they have antimicrobial and insecticide properties …

[HTML][HTML] Anti-liver cancer activity in vitro and in vivo induced by 2-pyridyl 2, 3-thiazole derivatives

TD dos Santos Silva, LM Bomfim… - Toxicology and applied …, 2017 - Elsevier
A total of 24 hybrid compounds containing pyridyl and 1, 3-thiazole moieties were screened
against HL-60 (leukemia), MCF-7 (breast adenocarcinoma), HepG2 (hepatocellular …

Halogenated aromatic thiosemicarbazones as potent inhibitors of tyrosinase and melanogenesis

K Hałdys, W Goldeman, M Jewgiński, E Wolińska… - Bioorganic …, 2020 - Elsevier
A set of 21 halogenated thiosemicarbazones (TSCs) have been synthesized and its
inhibitory properties toward activity diphenolase of mushroom tyrosinase and their ability to …

Cladophialophora bantiana metabolites are efficient in the larvicidal and ovicidal control of Aedes aegypti, and Culex quinquefasciatus and have low toxicity in …

C Ragavendran, G Balasubramani, C Tijo… - Science of the Total …, 2022 - Elsevier
Mosquitoes' current insecticide resistance status in available public health insecticides is a
serious threat to mosquito control initiatives. Microbe-based control agents provide an …

Synthesis and evaluation of novel 1, 3, 4-thiadiazole--fluoroquinolone hybrids as antibacterial, antituberculosis, and anticancer agents

A Demirci, KG KARAYEL, E Tatar… - Turkish Journal of …, 2018 - journals.tubitak.gov.tr
Abstract A series of 5-substituted-1, 3, 4-thiadiazole-based fluoroquinolone derivatives were
designed as potential antibacterial and anticancer agents using a molecular hybridization …