Systematic Review of Roles of Arecoline and Arecoline N-Oxide in Oral Cancer and Strategies to Block Carcinogenesis

AMS Ko, HP Tu, YC Ko - Cells, 2023 - mdpi.com
Betel quid and areca nut are complex mixture carcinogens, but little is known about whether
their derived single-agent arecoline or arecoline N-oxide (ANO) is carcinogenic, and the …

Smoking cessation and risk of esophageal cancer by histological type: systematic review and meta-analysis

QL Wang, SH Xie, WT Li… - JNCI: Journal of the …, 2017 - academic.oup.com
Background Tobacco smoking strongly increases risk of esophageal squamous cell
carcinoma and moderately increases risk of esophageal adenocarcinoma. How smoking …

Betel quid chewing and the risk of oral and oropharyngeal cancers: a meta‐analysis with implications for cancer control

N Guha, S Warnakulasuriya… - … journal of cancer, 2014 - Wiley Online Library
We conducted a random‐effects meta‐analysis of 50 publications assessing the relationship
between oral/oropharyngeal cancer and chewing betel quid, with (BQ+ T) or without added …

The magnitude of tobacco smoking-betel quid chewing-alcohol drinking interaction effect on oral cancer in South-East Asia. A meta-analysis of observational studies

S Petti, M Masood, C Scully - PloS one, 2013 - journals.plos.org
Tobacco smoking, betel quid chewing and alcohol drinking are oral cancer risk factors.
Observational studies unanimously report that oral cancer risk in smoking-drinking-chewing …

中国食管癌病因学, 筛查及早期诊断研究进展

杨欢, 孙宛怡, 王建炳, 王晓坤, 张锦雨, 范金虎… - 肿瘤防治研究, 2022 - zlfzyj.com
食管癌是全球最致命的癌症之一, CLOBOCAN 2020 显示, 全球约有60 万食管癌新发病例,
死亡约54 万例, 而全球近一半的食管癌发病和死亡病例发生在我国. 过去二十年中我国食管癌的 …

Betel-quid dependence and oral potentially malignant disorders in six Asian countries

CH Lee, AMS Ko, CF Yen, KS Chu, YJ Gao… - The British Journal of …, 2012 - cambridge.org
BackgroundDespite gradual understanding of the multidimensional health consequences of
betel-quid chewing, information on the effects of dependent use is scant. AimsTo investigate …

Areca nut chewing and esophageal squamous-cell carcinoma risk in Asians: A meta-analysis of case–control studies

S Akhtar - Cancer Causes & Control, 2013 - Springer
Purpose This meta-anlaysis quantitatively assessed an overall independent association
between areca nut chewing and esophageal squamous-cell carcinoma in Asians. Methods …

Population burden of betel quid abuse and its relation to oral premalignant disorders in South, Southeast, and East Asia: an Asian Betel-quid Consortium Study

CH Lee, A Min-Shan Ko… - … journal of public …, 2012 - ajph.aphapublications.org
Objectives. We investigated the population burden of betel quid abuse and its related impact
on oral premalignant disorders (OPDs) in South, Southeast, and East Asia. Methods. The …

Betel‐quid dependence domains and syndrome associated with betel‐quid ingredients among chewers: an A sian multi‐country evidence

CH Lee, SL Chiang, AMS Ko, CH Hua, MH Tsai… - …, 2014 - Wiley Online Library
Aims Betel‐quid (BQ) contains biologically psychoactive ingredients; however, data are
limited concerning the symptoms and syndrome of BQ dependence among chewers. The …

Association of DSM-5 betel-quid use disorder with oral potentially malignant disorder in 6 betel-quid endemic Asian populations

CH Lee, AMS Ko, FM Yang, CC Hung… - JAMA …, 2018 - jamanetwork.com
Importance Betel-quid (BQ) is the fourth most popular psychoactive agent worldwide. An
emerging trend across Asia is the addictive consumption of BQ, which is associated with oral …