The skin is the largest organ of the human body and prone to various diseases, including
cancer; thus, provides the first line of defense against exogenous biological and non …

Cutaneous squamous cell carcinoma (cSCC) is a disease with globally rising incidence and
poor prognosis for patients with advanced or metastatic disease. Epithelial-mesenchymal …

Monocytes have been reported to be important mediators of the protective effect of exercise
against the development of Alzheimer's disease (AD). This study aims explored the …

Abstract Sirtuin 6 (SIRT6) has a critical role in cutaneous Squamous Cell Carcinoma
(cSCC): SIRT6 silencing in skin SCC cells has pro-differentiating effects and SIRT6 deletion …

In the course of identifying the molecular mechanism that is related to strong cell‐cell
adhesion in stratified structures of the squamous epithelium, calmodulin‐like protein 5 …

Krüppel-like factors (KLFs) are a group of DNA-binding transcriptional regulators with
multiple essential functions in various cellular processes, including proliferation, migration …

Idiopathic pulmonary fibrosis (IPF) is a serious lung disease that involved the myofibroblast
differentiation of lung resident mesenchymal stem cells (LR-MSCs). However, the specific …

S-phase kinase-associated protein 2 (Skp2) is an F-box protein overexpressed in human
cancers and linked with poor prognosis. It triggers cancer pathogenesis, including stemness …

The transcription factor Twist1 has been reported to be essential for the formation and
invasiveness of chemically induced tumors in mouse skin. However, the impact of …

Cutaneous squamous cell carcinoma (cSCC) represents an important clinical problem
requiring novel approaches for both prevention and treatment. The transcription factor, Twist …