Natural polymer-based hydrogels: From polymer to biomedical applications

L Zhao, Y Zhou, J Zhang, H Liang, X Chen, H Tan - Pharmaceutics, 2023 - mdpi.com
Hydrogels prepared from natural polymer have attracted extensive attention in biomedical
fields such as drug delivery, wound healing, and regenerative medicine due to their good …

Organ-on-chip models for infectious disease research

R Alonso-Roman, AS Mosig, MT Figge… - Nature …, 2024 - nature.com
Research on microbial pathogens has traditionally relied on animal and cell culture models
to mimic infection processes in the host. Over recent years, developments in microfluidics …

Microphysiological systems for human aging research

S Park, TC Laskow, J Chen, P Guha, B Dawn… - Aging …, 2024 - Wiley Online Library
Recent advances in microphysiological systems (MPS), also known as organs‐on‐a‐chip
(OoC), enable the recapitulation of more complex organ and tissue functions on a smaller …

Musculoskeletal Organs‐on‐Chips: An Emerging Platform for Studying the Nanotechnology–Biology Interface

Y Wang, P Yung, G Lu, Y Liu, C Ding, C Mao… - Advanced …, 2024 - Wiley Online Library
Nanotechnology‐based approaches are promising for the treatment of musculoskeletal
(MSK) disorders, which present significant clinical burdens and challenges, but their clinical …

In vitro immunity: an overview of immunocompetent organ-on-chip models

AI Morrison, MJ Sjoerds, LA Vonk, S Gibbs… - Frontiers in …, 2024 - frontiersin.org
Impressive advances have been made to replicate human physiology in vitro over the last
few years due to the growth of the organ-on-chip (OoC) field in both industrial and academic …

A Versatile Microfluidic Platform for Extravasation Studies Based on DNA Origami—Cell Interactions

M García‐Chamé, P Wadhwani, J Pfeifer… - Angewandte …, 2024 - Wiley Online Library
The adhesion of circulating tumor cells (CTCs) to the endothelial lumen and their
extravasation to surrounding tissues are crucial in the seeding of metastases and remain the …

A simulated microgravity-oriented AIE probe-ECM hydrogel-integrated chip for cell culture and superoxide anion radical detection

Z Su, B Liu, J Dai, M Han, JC Lai, S Wang… - Biosensors and …, 2024 - Elsevier
Human space activities have been continuously increasing. Astronauts experiencing
spaceflight are faced with health problems caused by special space environments such as …

A Review: Early Detection of Oral Cancer Biomarkers Using Microfluidic Colorimetric Point-of-Care Devices

A Balapure, S Goel, SK Dubey, A Javed… - Analytical …, 2024 - pubs.rsc.org
Oral squamous cell carcinoma (OSCC) is a major among the head and neck cancers. OSCC
constitutes 90% of the head and neck malignancies. The delayed identification of oral …

Heart-on-a-chip systems: disease modeling and drug screening applications

D Butler, DR Reyes - Lab on a Chip, 2024 - pubs.rsc.org
Cardiovascular disease (CVD) is the leading cause of death worldwide, casting a
substantial economic footprint and burdening the global healthcare system. Historically, pre …

Integrated Microfluidics for Single‐Cell Separation and On‐Chip Analysis: Novel Applications and Recent Advances

H Kutluk, M Viefhues, I Constantinou - Small Science, 2024 - Wiley Online Library
From deciphering infection and disease mechanisms to identifying novel biomarkers and
personalizing treatments, the characteristics of individual cells can provide significant …