The sequence of the human genome

JC Venter, MD Adams, EW Myers, PW Li, RJ Mural… - science, 2001 - science.org
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …

The Genome Sequence of Drosophila melanogaster

MD Adams, SE Celniker, RA Holt, CA Evans… - Science, 2000 - science.org
The fly Drosophila melanogaster is one of the most intensively studied organisms in biology
and serves as a model system for the investigation of many developmental and cellular …

Genome-wide prediction of metabolic enzymes, pathways, and gene clusters in plants

P Schläpfer, P Zhang, C Wang, T Kim, M Banf… - Plant …, 2017 - academic.oup.com
Plant metabolism underpins many traits of ecological and agronomic importance. Plants
produce numerous compounds to cope with their environments but the biosynthetic …

The coffee genome provides insight into the convergent evolution of caffeine biosynthesis

F Denoeud, L Carretero-Paulet, A Dereeper, G Droc… - science, 2014 - science.org
Coffee is a valuable beverage crop due to its characteristic flavor, aroma, and the stimulating
effects of caffeine. We generated a high-quality draft genome of the species Coffea …

Analysis of the genome sequence of the flowering plant Arabidopsis thaliana

… genomeanalysis@ tgr. org genomeanalysis@ gsf. de - nature, 2000 - nature.com
The flowering plant Arabidopsis thaliana is an important model system for identifying genes
and determining their functions. Here we report the analysis of the genomic sequence of …

Predicting subcellular localization of proteins based on their N-terminal amino acid sequence

O Emanuelsson, H Nielsen, S Brunak… - Journal of molecular …, 2000 - Elsevier
A neural network-based tool, TargetP, for large-scale subcellular location prediction of newly
identified proteins has been developed. Using N-terminal sequence information only, it …

Arabidopsis Transcription Factors: Genome-Wide Comparative Analysis Among Eukaryotes

JL Riechmann, J Heard, G Martin, L Reuber, CZ Jiang… - science, 2000 - science.org
The completion of the Arabidopsis thaliana genome sequence allows a comparative
analysis of transcriptional regulators across the three eukaryotic kingdoms. Arabidopsis …

Sequence-related amplified polymorphism (SRAP), a new marker system based on a simple PCR reaction: its application to mapping and gene tagging in Brassica

G Li, CF Quiros - Theoretical and applied genetics, 2001 - Springer
We developed a simple marker technique called sequence-related amplified polymorphism
(SRAP) aimed for the amplification of open reading frames (ORFs). It is based on two-primer …

Endosymbiotic gene transfer: organelle genomes forge eukaryotic chromosomes

JN Timmis, MA Ayliffe, CY Huang, W Martin - Nature reviews genetics, 2004 - nature.com
Genome sequences reveal that a deluge of DNA from organelles has constantly been
bombarding the nucleus since the origin of organelles. Recent experiments have shown that …

ANEW APPROACH TO DECODING LIFE: Systems Biology

T Ideker, T Galitski, L Hood - Annual review of genomics and …, 2001 - annualreviews.org
▪ Abstract Systems biology studies biological systems by systematically perturbing them
(biologically, genetically, or chemically); monitoring the gene, protein, and informational …