Viruses and other selfish genetic elements are dominant entities in the biosphere, with
respect to both physical abundance and genetic diversity. Various selfish elements …

While single-stranded DNA (ssDNA) was once thought to be a relatively rare genomic
architecture for viruses, modern metagenomics sequencing has revealed circular ssDNA …

The perpetually increasing rate at which viral full-genome sequences are being determined
is creating a pressing demand for computational tools that will aid the objective classification …

Background Viruses strongly influence microbial population dynamics and ecosystem
functions. However, our ability to quantitatively evaluate those viral impacts is limited to the …

Most human emerging infectious diseases originate from wildlife and bats are a major
reservoir of viruses, a few of which have been highly pathogenic to humans. In some regions …

Metagenomics has revealed the existence of numerous uncharacterized viral lineages,
which are referred to as viral “dark matter.” However, our knowledge regarding viral …

Eukaryotic circular single-stranded DNA (ssDNA) viruses were known only to infect plants
and vertebrates until the discovery of the isolated DNA mycovirus from the fungus Sclerotinia …

Snow and ice environments cover up to 21% of the Earth's surface. They have been
regarded as extreme environments because of their low temperatures, high UV irradiation …

There is growing interest in characterizing the viromes of diverse mammalian species,
particularly in the context of disease emergence. However, little is known about virome …

Over the last five years next-generation sequencing has become a cost effective and
efficient method for identifying known and unknown microorganisms. Access to this …