Aquaporins (AQPs) are integral membrane proteins and found in all living organisms from
bacteria to human. AQPs mainly involved in the transmembrane diffusion of water as well as …

Plasma membrane curvature is an important factor in the regulation of cellular phenotype
and is critical for various cellular activities including the shedding of extracellular vesicles …

To maintain optimal fitness, a cell must balance the risk of inadequate energy reserve for
response to a potentially fatal perturbation against the long-term cost of maintaining high …

Aquaporin (AQP) water channels are pivotal to renal water handling and therefore in the
regulation of body water homeostasis. However, beyond the kidney, AQPs facilitate water …

Stomach and intestines are involved in the secretion of gastrointestinal fluids and the
absorption of nutrients and fluids, which ensure normal gut functions. Aquaporin water …

Endothelial cells (ECs) make up the lining of our blood vessels and they ensure optimal
nutrient and oxygen delivery to the parenchymal tissue. In response to oxygen and/or …

Background Cancer cells, and a variety of normal cells, exhibit aerobic glycolysis, high rates
of glucose fermentation in the presence of normal oxygen concentrations, also known as the …

Increasing evidence suggests that the water/glycerol channel aquaporin-3 (AQP3) plays a
pivotal role in cancer metastasis. AQP3 knockout mice were resistant to skin tumor formation …

Both direct and long-range interactions between pathogenic Pseudomonas aeruginosa
bacteria and their eukaryotic hosts are important in the outcome of infections. For cell-to-cell …

The alteration of glucose metabolism is one of the first biochemical characteristics
associated with cancer cells since most of these cells increase glucose consumption and …