Accelerating the integration of ChatGPT and other large‐scale AI models into biomedical research and healthcare
DQ Wang, LY Feng, JG Ye, JG Zou… - MedComm–Future …, 2023 - Wiley Online Library
Large‐scale artificial intelligence (AI) models such as ChatGPT have the potential to
improve performance on many benchmarks and real‐world tasks. However, it is difficult to …
improve performance on many benchmarks and real‐world tasks. However, it is difficult to …
Growing ecosystem of deep learning methods for modeling protein–protein interactions
JR Rogers, G Nikolényi… - … Engineering, Design and …, 2023 - academic.oup.com
Numerous cellular functions rely on protein–protein interactions. Efforts to comprehensively
characterize them remain challenged however by the diversity of molecular recognition …
characterize them remain challenged however by the diversity of molecular recognition …
Combining pairwise structural similarity and deep learning interface contact prediction to estimate protein complex model accuracy in CASP15
Estimating the accuracy of quaternary structural models of protein complexes and
assemblies (EMA) is important for predicting quaternary structures and applying them to …
assemblies (EMA) is important for predicting quaternary structures and applying them to …
ComplexQA: A deep graph learning approach for protein complex structure assessment
Motivation In recent years, the end-to-end deep learning method for single-chain protein
structure prediction has achieved high accuracy. For example, the state-of-the-art method …
structure prediction has achieved high accuracy. For example, the state-of-the-art method …
Protein structure accuracy estimation using geometry‐complete perceptron networks
Estimating the accuracy of protein structural models is a critical task in protein bioinformatics.
The need for robust methods in the estimation of protein model accuracy (EMA) is prevalent …
The need for robust methods in the estimation of protein model accuracy (EMA) is prevalent …
Chemical cross-linking and mass spectrometry enabled systems-level structural biology
L Botticelli, AA Bakhtina, NK Kaiser, A Keller… - Current Opinion in …, 2024 - Elsevier
Structural information on protein–protein interactions (PPIs) is essential for improved
understanding of regulatory interactome networks that confer various physiological and …
understanding of regulatory interactome networks that confer various physiological and …
[HTML][HTML] AlphaFold Accurately Predicts the Structure of Ribosomally Synthesized and Post-Translationally Modified Peptide Biosynthetic Enzymes
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a growing
class of natural products biosynthesized from a genetically encoded precursor peptide. The …
class of natural products biosynthesized from a genetically encoded precursor peptide. The …
[HTML][HTML] EGG: Accuracy Estimation of Individual Multimeric Protein Models Using Deep Energy-Based Models and Graph Neural Networks
Reliable and accurate methods of estimating the accuracy of predicted protein models are
vital to understanding their respective utility. Discerning how the quaternary structure …
vital to understanding their respective utility. Discerning how the quaternary structure …
[HTML][HTML] A Survey of Deep Learning Methods for Estimating the Accuracy of Protein Quaternary Structure Models
The quality prediction of quaternary structure models of a protein complex, in the absence of
its true structure, is known as the Estimation of Model Accuracy (EMA). EMA is useful for …
its true structure, is known as the Estimation of Model Accuracy (EMA). EMA is useful for …
Combining pairwise structural similarity and deep learning interface contact prediction to estimate protein complex model accuracy in CASP15.
Estimating the accuracy of quaternary structural models of protein complexes and
assemblies (EMA) is important for predicting quaternary structures and applying them to …
assemblies (EMA) is important for predicting quaternary structures and applying them to …