Bacteria in cancer initiation, promotion and progression

G El Tekle, WS Garrett - Nature Reviews Cancer, 2023 - nature.com
Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …

The microbiome and human cancer

GD Sepich-Poore, L Zitvogel, R Straussman, J Hasty… - Science, 2021 - science.org
BACKGROUND Historical accounts linking cancer and microbes date as early as four
millennia ago. After establishment of the germ theory of infectious diseases, clinical research …

Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer

JL Galeano Niño, H Wu, KD LaCourse… - Nature, 2022 - nature.com
The tumour-associated microbiota is an intrinsic component of the tumour microenvironment
across human cancer types,. Intratumoral host–microbiota studies have so far largely relied …

[HTML][HTML] Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer

A Fu, B Yao, T Dong, Y Chen, J Yao, Y Liu, H Li, H Bai… - Cell, 2022 - cell.com
Tumor-resident intracellular microbiota is an emerging tumor component that has been
documented for a variety of cancer types with unclear biological functions. Here, we …

[HTML][HTML] Microbiome and cancer

N Cullin, CA Antunes, R Straussman… - Cancer Cell, 2021 - cell.com
The human microbiome constitutes a complex multikingdom community that symbiotically
interacts with the host across multiple body sites. Host-microbiome interactions impact …

Targeting metastatic cancer

K Ganesh, J Massague - Nature medicine, 2021 - nature.com
Despite recent therapeutic advances in cancer treatment, metastasis remains the principal
cause of cancer death. Recent work has uncovered the unique biology of metastasis …

The gut microbial metabolite formate exacerbates colorectal cancer progression

D Ternes, M Tsenkova, VI Pozdeev, M Meyers… - Nature …, 2022 - nature.com
The gut microbiome is a key player in the immunomodulatory and protumorigenic
microenvironment during colorectal cancer (CRC), as different gut-derived bacteria can …

Identification of bacteria-derived HLA-bound peptides in melanoma

S Kalaora, A Nagler, D Nejman, M Alon, C Barbolin… - Nature, 2021 - nature.com
A variety of species of bacteria are known to colonize human tumours,,,,,,,,,–, proliferate
within them and modulate immune function, which ultimately affects the survival of patients …

An umbrella review of the evidence linking oral health and systemic noncommunicable diseases

J Botelho, P Mascarenhas, J Viana, L Proença… - Nature …, 2022 - nature.com
Oral diseases are highly prevalent worldwide. Recent studies have been supporting a
potential bidirectional association of oral diseases with systemic noncommunicable …

Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy

L Yang, A Li, Y Wang, Y Zhang - Signal transduction and targeted …, 2023 - nature.com
Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in
human health. An altered microbiome can be associated with complex diseases …