Recent advances in the development of therapeutic peptides

J Fetse, S Kandel, UF Mamani, K Cheng - Trends in Pharmacological …, 2023 - cell.com
Peptides have unique characteristics that make them highly desirable as therapeutic agents.
The physicochemical and proteolytic stability profiles determine the therapeutic potential of …

Marine pharmacology in 2018: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis and antiviral activities; …

AMS Mayer, ML Pierce, K Howe, AD Rodríguez… - Pharmacological …, 2022 - Elsevier
The 2018 marine pharmacology literature review represents a continuation of the previous
11 reviews of a series initiated in 1998. Preclinical marine pharmacology research during …

Effect of Food Preparations on In Vitro Bioactivities and Chemical Components of Fucus vesiculosus

R André, L Guedes, R Melo, L Ascensão, R Pacheco… - Foods, 2020 - mdpi.com
Fucus vesiculosus is a brown macroalgae used in food and generally considered safe to be
consumed, according to EU Directive (EC 258/97). The aim of this study is to analyze the …

Bruceine D acts as a potential insecticide by antagonizing 20E–EcR/USP signal transduction

D Chen, K Li, B Wang, H Chen, H Jiang… - Journal of Agricultural …, 2023 - ACS Publications
Bruceine D (BD) is an effective insecticidal compound found in the Chinese herb Brucea
javanica (L.) Merr. BD inhibits the growth and metamorphosis of Plutella xylostella and …

[HTML][HTML] Toxin-like peptides in plasma, urine and faecal samples from COVID-19 patients

C Brogna, S Cristoni, M Petrillo, M Querci… - …, 2021 - ncbi.nlm.nih.gov
Background: SARS-CoV-2 that causes COVID-19 disease and led to the pandemic currently
affecting the world has been broadly investigated. Different studies have been performed to …

Acetylcholinesterase and butyrylcholinesterase inhibitory activities of antioxidant peptides obtained from enzymatic pea protein hydrolysates and their ultrafiltration …

ND Asen, RE Aluko - Journal of Food Biochemistry, 2022 - Wiley Online Library
This study optimized the enzymatic hydrolysis of yellow field pea proteins using alcalase
(ACH), chymotrypsin (CHH), flavourzyme (FZH), pancreatin (PCH), pepsin (PEH), and …

Sturgeon (Acipenser schrenckii) spinal cord peptides: Antioxidative and acetylcholinesterase inhibitory efficacy and mechanisms

X Zu, Q Zhao, W Liu, L Guo, T Liao, J Cai, H Li - Food chemistry, 2024 - Elsevier
Providing antioxidants and targeting acetylcholinesterase (AChE) are key strategies in
treating neurocognitive dysfunction. In this study, bioactive sturgeon (Acipenser schrenckii) …

A biological clean processing approach for the valorization of speckled shrimp Metapenaeus monoceros by-product as a source of bioactive compounds

S Mechri, I Sellem, K Bouacem, F Jabeur… - … Science and Pollution …, 2020 - Springer
The efficiency of the proteolytic strain Anoxybacillus kamchatkensis M1V in the fermentation
of speckled shrimp by-product was investigated for the recovery of a deproteinized bioactive …

Proposing novel natural compounds against Alzheimer's disease targeting acetylcholinesterase

M Girgin, S Isik, N Kantarci-Carsibasi - Plos one, 2023 - journals.plos.org
Alzheimer's disease (AD) is a neurodegenerative disorder considered as a global public
health threat influencing many people. Despite the concerning rise in the affected …

PyPLIF HIPPOS: A molecular interaction fingerprinting tool for docking results of AutoDock Vina and PLANTS

EP Istyastono, M Radifar, N Yuniarti… - Journal of Chemical …, 2020 - ACS Publications
We describe here our tool named PyPLIF HIPPOS, which was newly developed to analyze
the docking results of AutoDock Vina and PLANTS. Its predecessor, PyPLIF (https://github …